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扩散磁共振成像在帕金森病及与非典型帕金森综合征鉴别诊断中的作用

The role of diffusion magnetic resonance imaging in Parkinson's disease and in the differential diagnosis with atypical parkinsonism.

作者信息

de Oliveira Romulo Varella, Pereira João Santos

机构信息

Full Member of the Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR), Masters Student in the Graduate Program in Medical Sciences at the Faculdade de Ciências Médicas da Universidade do Estado do Rio de Janeiro (FCM-UERJ), MD, Radiologist at the Hospital Universitário Pedro Ernesto (HUPE) and at the Clínica Alta Excelência Diagnóstica (DASA), Rio de Janeiro, RJ, Brazil.

PhD, Full Member of the Academia Brasileira de Neurologia (ABN), Associate Professor, Coordinator of the Movement Disorders Sector of the Neurology Department of the Hospital Universitário Pedro Ernesto da Universidade do Estado do Rio de Janeiro (HUPE-UERJ), Rio de Janeiro, RJ, Brazil.

出版信息

Radiol Bras. 2017 Jul-Aug;50(4):250-257. doi: 10.1590/0100-3984.2016-0073.

DOI:10.1590/0100-3984.2016-0073
PMID:28894333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5586516/
Abstract

Parkinson's disease is one of the most common neurodegenerative diseases. Clinically, it is characterized by motor symptoms. Parkinson's disease should be differentiated from atypical parkinsonism conditions. Conventional magnetic resonance imaging is the primary imaging method employed in order to facilitate the differential diagnosis, and its role has grown after the development of advanced techniques such as diffusion-weighted imaging. The purpose of this article was to review the role of magnetic resonance imaging in Parkinson's disease and in the differential diagnosis with atypical parkinsonism, emphasizing the diffusion technique.

摘要

帕金森病是最常见的神经退行性疾病之一。临床上,其特征为运动症状。帕金森病应与非典型帕金森综合征相鉴别。传统磁共振成像为便于鉴别诊断所采用的主要成像方法,且在诸如扩散加权成像等先进技术发展之后其作用有所增强。本文旨在综述磁共振成像在帕金森病及其与非典型帕金森综合征鉴别诊断中的作用,重点阐述扩散技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e552/5586516/d02118dbb0ed/rb-50-04-0250-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e552/5586516/80a0c19840be/rb-50-04-0250-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e552/5586516/4835061b28c0/rb-50-04-0250-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e552/5586516/d02118dbb0ed/rb-50-04-0250-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e552/5586516/80a0c19840be/rb-50-04-0250-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e552/5586516/4835061b28c0/rb-50-04-0250-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e552/5586516/d02118dbb0ed/rb-50-04-0250-g03.jpg

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引用本文的文献

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Parkinson's disease and atypical parkinsonism: the importance of magnetic resonance imaging as a potential biomarker.

本文引用的文献

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A novel method for evaluating brain function and microstructural changes in Parkinson's disease.一种评估帕金森病脑功能和微观结构变化的新方法。
Neural Regen Res. 2015 Dec;10(12):2025-32. doi: 10.4103/1673-5374.172322.
2
Accuracy of clinical diagnosis of Parkinson disease: A systematic review and meta-analysis.帕金森病临床诊断的准确性:一项系统评价和荟萃分析。
Neurology. 2016 Feb 9;86(6):566-76. doi: 10.1212/WNL.0000000000002350. Epub 2016 Jan 13.
3
Multimodal MRI assessment of nigro-striatal pathway in multiple system atrophy and Parkinson disease.
帕金森病与非典型帕金森综合征:磁共振成像作为潜在生物标志物的重要性
Radiol Bras. 2017 Jul-Aug;50(4):V-VI. doi: 10.1590/0100-3984.2017.50.4e1.
多模态 MRI 评估多系统萎缩和帕金森病的黑质纹状体通路。
Mov Disord. 2016 Mar;31(3):325-34. doi: 10.1002/mds.26471. Epub 2015 Dec 17.
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Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease?灰、白质成像:早期帕金森病认知障碍的生物标志物?
Mov Disord. 2016 Jan;31(1):103-10. doi: 10.1002/mds.26312. Epub 2015 Jul 22.
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Fractional anisotropy in the substantia nigra in Parkinson's disease: a complex picture.帕金森病中黑质的分数各向异性:一幅复杂的图景。
Eur J Neurol. 2015 Oct;22(10):1408-14. doi: 10.1111/ene.12760. Epub 2015 Jun 29.
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Magnetic resonance imaging markers for early diagnosis of Parkinson's disease.用于帕金森病早期诊断的磁共振成像标志物。
Neural Regen Res. 2012 Mar 15;7(8):611-9. doi: 10.3969/j.issn.1673-5374.2012.08.009.
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Diffusion tensor imaging parameters' changes of cerebellar hemispheres in Parkinson's disease.帕金森病中小脑半球的扩散张量成像参数变化
Neuroradiology. 2015 Mar;57(3):327-34. doi: 10.1007/s00234-014-1473-5. Epub 2014 Dec 6.
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Atypical parkinsonism: diagnosis and treatment.非典型帕金森病:诊断与治疗
Neurol Clin. 2015 Feb;33(1):39-56. doi: 10.1016/j.ncl.2014.09.012.
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A review of the use of magnetic resonance imaging in Parkinson's disease.磁共振成像在帕金森病中的应用综述。
Ther Adv Neurol Disord. 2014 Jul;7(4):206-20. doi: 10.1177/1756285613511507.
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Brain MRI in Parkinson's disease.帕金森病的脑部磁共振成像
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