精神分裂症患者与正常对照在图片观看任务中的视动表现。

Visuomotor performance of schizophrenic patients and normal controls in a picture viewing task.

作者信息

Gaebel W, Ulrich G, Frick K

机构信息

Psychiatrische Klinik and Poliklinik, Freien Universität Berlin, F.R.G.

出版信息

Biol Psychiatry. 1987 Oct;22(10):1227-37. doi: 10.1016/0006-3223(87)90030-8.

DOI:10.1016/0006-3223(87)90030-8

PMID:2889478

Abstract

The eye movements of 20 partially remitted schizophrenic outpatients (ICD-9) under neuroleptic maintenance medication and those of 20 normal controls were recorded using corneal reflection pupil-center measurement. The visuomotor performance during a 1-min picture viewing task was studied on the basis of several eye movement parameters. Clinical evaluation comprised self-ratings (Frankfort Complaint Questionnaire) and observer ratings (BPRS, CGI, GAS), as well as recording of current daily neuroleptic dosage (mg CPZ). The main results are that schizophrenics differ from normals in their correlational pattern of fixation- and movement-related parameters, reflecting two opposite viewing styles in schizophrenics: staring and extensive scanning. Both styles are differently related to clinical symptomatology. There was no strongly marked relationship with neuroleptic dosage.

摘要

采用角膜反射瞳孔中心测量法，记录了20名在接受抗精神病药物维持治疗的部分缓解期精神分裂症门诊患者（国际疾病分类第九版）以及20名正常对照者的眼球运动。基于多项眼球运动参数，研究了在1分钟图片观看任务期间的视运动表现。临床评估包括自评（法兰克福症状问卷）和观察者评分（简明精神病评定量表、临床总体印象量表、大体评定量表），以及记录当前每日抗精神病药物剂量（氯丙嗪毫克数）。主要结果是，精神分裂症患者在注视和运动相关参数的相关模式上与正常人不同，这反映出精神分裂症患者有两种相反的观看方式：凝视和广泛扫描。这两种方式与临床症状学的关系各不相同。与抗精神病药物剂量没有明显的强关联。