Swanson Kenneth D, Worth Anne L, Glish Gary L
Department of Chemistry, Caudill Laboratories, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-3290, USA.
J Am Soc Mass Spectrom. 2018 Feb;29(2):297-303. doi: 10.1007/s13361-017-1776-y. Epub 2017 Sep 11.
A simple design for an open port sampling interface coupled to electrospray ionization (OPSI-ESI) is presented for the analysis of organic aerosols. The design uses minimal modifications to a Bruker electrospray (ESI) emitter to create a continuous flow, self-aspirating open port sampling interface. Considerations are presented for introducing aerosol to the open port sampling interface including aerosol gas flow and solvent flow rates. The device has been demonstrated for use with an aerosol of nicotine as well as aerosol formed in the pyrolysis of biomass. Upon comparison with extractive electrospray ionization (EESI), this device has similar sensitivity with increased reproducibility by nearly a factor of three. The device has the form factor of a standard Bruker/Agilent ESI emitter and can be used without any further instrument modifications. Graphical Abstract ᅟ.
本文介绍了一种用于分析有机气溶胶的开放式端口采样接口与电喷雾电离相结合的简单设计（OPSI-ESI）。该设计对布鲁克电喷雾（ESI）发射器进行了最小程度的修改，以创建一个连续流动、自吸式的开放式端口采样接口。文中介绍了将气溶胶引入开放式端口采样接口时的注意事项，包括气溶胶气体流速和溶剂流速。该装置已被证明可用于尼古丁气溶胶以及生物质热解过程中形成的气溶胶。与萃取电喷雾电离（EESI）相比，该装置具有相似的灵敏度，重现性提高了近三倍。该装置具有标准布鲁克/安捷伦ESI发射器的外形尺寸，无需对仪器进行任何进一步修改即可使用。图形摘要ᅟ。
