低收入国家的丙型肝炎与基因组数据缺失：消除之路上的障碍？ - Suppr

Hepatitis C and the absence of genomic data in low-income countries: a barrier on the road to elimination?

作者信息

Niebel Marc, Singer Joshua B, Nickbakhsh Sema, Gifford Robert J, Thomson Emma C

机构信息

MRC-University of Glasgow Centre for Virus Research, Institute of Infection, Inflammation and Immunity, Glasgow G61 1QH, UK.

出版信息

Lancet Gastroenterol Hepatol. 2017 Oct;2(10):700-701. doi: 10.1016/S2468-1253(17)30257-1.

DOI:10.1016/S2468-1253(17)30257-1

PMID:28895545

Abstract

摘要

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Hepatitis C and the absence of genomic data in low-income countries: a barrier on the road to elimination?低收入国家的丙型肝炎与基因组数据缺失：消除之路上的障碍？

Lancet Gastroenterol Hepatol. 2017 Oct;2(10):700-701. doi: 10.1016/S2468-1253(17)30257-1.

Nonstructural protein 5A/P32 deletion after failure of ledipasvir/sofosbuvir in hepatitis C virus genotype 1b infection.在丙型肝炎病毒1b型感染中，来迪派韦/索磷布韦治疗失败后非结构蛋白5A/P32缺失

Hepatology. 2018 Jul;68(1):380-383. doi: 10.1002/hep.29836. Epub 2018 May 14.

[Virus factors determining the outcome of IFN treatment for chronic hepatitis C].[决定慢性丙型肝炎干扰素治疗结局的病毒因素]

Nihon Rinsho. 2004 Jul;62 Suppl 7(Pt 1):474-80.

Diagnosis of hepatitis C virus genotype 2k/1b needs NS5B sequencing.丙型肝炎病毒2k/1b基因型的诊断需要对NS5B进行测序。

Int J Infect Dis. 2015 Dec;41:1-2. doi: 10.1016/j.ijid.2015.10.010. Epub 2015 Oct 17.

A public health approach to hepatitis C control in low- and middle-income countries.低收入和中等收入国家丙型肝炎防控的公共卫生方法。

PLoS Med. 2015 Mar 10;12(3):e1001795. doi: 10.1371/journal.pmed.1001795. eCollection 2015 Mar.

Naturally occurring NS3 resistance-associated variants in hepatitis C virus genotype 1: Their relevance for developing countries.丙型肝炎病毒1型中自然存在的与NS3耐药相关的变异体：它们对发展中国家的相关性。

Virus Res. 2016 Sep 2;223:140-6. doi: 10.1016/j.virusres.2016.07.008. Epub 2016 Jul 19.

Mechanism of interferon resistance in hepatitis C.

Lancet. 2001 Nov 17;358(9294):1662-4. doi: 10.1016/S0140-6736(01)06728-9.

NS5A sequences of hepatitis C virus genotype 1 and interferon resistance: where are we?丙型肝炎病毒1型的NS5A序列与干扰素耐药性：我们目前的进展如何？

J Infect Dis. 2008 Jul 1;198(1):154-5. doi: 10.1086/588709.

Mutations in the nonstructural 5A region of hepatitis C virus and response of chronic hepatitis C to interferon alfa.丙型肝炎病毒非结构5A区域的突变与慢性丙型肝炎对干扰素α的反应

Gastroenterology. 1997 Aug;113(2):567-72. doi: 10.1053/gast.1997.v113.pm9247477.

Recent evidence of underestimated circulation of hepatitis C virus intergenotypic recombinant strain RF2k/1b in the Rhône-Alpes region, France, January to August 2014: implications for antiviral treatment.最近有证据表明，2014 年 1 月至 8 月法国罗纳-阿尔卑斯地区丙型肝炎病毒基因型间重组株 RF2k/1b 的循环被低估：对抗病毒治疗的影响。

Euro Surveill. 2014 Oct 30;19(43):20944. doi: 10.2807/1560-7917.es2014.19.43.20944.

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Microbiol Resour Announc. 2021 Oct 14;10(41):e0075521. doi: 10.1128/MRA.00755-21.

Non-epidemic HCV genotypes in low- and middle-income countries and the risk of resistance to current direct-acting antiviral regimens.低、中收入国家的非流行型 HCV 基因型与现有直接作用抗病毒治疗方案耐药的风险。

J Hepatol. 2021 Aug;75(2):462-473. doi: 10.1016/j.jhep.2021.04.045. Epub 2021 May 8.

Real-World Outcomes of Direct-Acting Antiviral Treatment and Retreatment in United Kingdom-Based Patients Infected With Hepatitis C Virus Genotypes/Subtypes Endemic in Africa.在英国感染非洲流行的丙型肝炎病毒基因型/亚型的患者中，直接作用抗病毒治疗和再治疗的真实世界结局。

J Infect Dis. 2022 Sep 21;226(6):995-1004. doi: 10.1093/infdis/jiab110.

Direct-Acting Antiviral Treatment for Hepatitis C Genotypes Uncommon in High-Income Countries: A Dutch Nationwide Cohort Study.高收入国家不常见的丙型肝炎基因型的直接抗病毒治疗：一项荷兰全国队列研究。

Open Forum Infect Dis. 2021 Jan 6;8(2):ofab006. doi: 10.1093/ofid/ofab006. eCollection 2021 Feb.

Efficacy and safety of sofosbuvir-based pangenotypic direct-acting antiviral agents for chronic hepatitis C patients without genotype determination: Real-world experience of a retrospective study.基于索磷布韦的泛基因型直接抗病毒药物用于未进行基因型测定的慢性丙型肝炎患者的疗效和安全性：一项回顾性研究的真实世界经验

Medicine (Baltimore). 2020 Oct 23;99(43):e22726. doi: 10.1097/MD.0000000000022726.

Analysis of genomic-length HBV sequences to determine genotype and subgenotype reference sequences.分析全基因组长度的 HBV 序列以确定基因型和亚型参考序列。

J Gen Virol. 2020 Mar;101(3):271-283. doi: 10.1099/jgv.0.001387.

Suboptimal SVR rates in African patients with atypical genotype 1 subtypes: Implications for global elimination of hepatitis C.非洲非典型 1 型基因型患者的 SVR 率不理想：对全球消除丙型肝炎的影响。

J Hepatol. 2019 Dec;71(6):1099-1105. doi: 10.1016/j.jhep.2019.07.025. Epub 2019 Aug 7.

Human cytomegalovirus genomics and transcriptomics through the lens of next-generation sequencing: revision and future challenges.从下一代测序视角看人类巨细胞病毒基因组学与转录组学：修订与未来挑战

Virus Genes. 2019 Apr;55(2):138-164. doi: 10.1007/s11262-018-1627-3. Epub 2019 Jan 2.

GLUE: a flexible software system for virus sequence data.GLUE：一个用于病毒序列数据的灵活软件系统。

BMC Bioinformatics. 2018 Dec 18;19(1):532. doi: 10.1186/s12859-018-2459-9.

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Hepatitis C and the absence of genomic data in low-income countries: a barrier on the road to elimination?

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