房水流出的结构和功能影像学：综述。
Structural and functional imaging of aqueous humour outflow: a review.
机构信息
Doheny Eye Institute, Los Angeles, California, USA.
Doheny Eye Centers, Department of Ophthalmology, David Geffen School of Medicine at University of California, Los Angeles, California, USA.
出版信息
Clin Exp Ophthalmol. 2018 Mar;46(2):158-168. doi: 10.1111/ceo.13064. Epub 2017 Oct 12.
Abstract
Maintaining healthy aqueous humour outflow (AHO) is important for intraocular cellular health and stable vision. Impairment of AHO can lead to increased intraocular pressure, optic nerve damage and concomitant glaucoma. An improved understanding of AHO will lead to improved glaucoma surgeries that enhance native AHO as well as facilitate the development of AHO-targeted pharmaceuticals. Recent AHO imaging has evolved to live human assessment and has focused on the structural evaluation of AHO pathways and the functional documentation of fluid flow. Structural AHO evaluation is predominantly driven by optical coherence tomography, and functional evaluation of flow is performed using various methods, including aqueous angiography. Advances in structural and functional evaluation of AHO are reviewed with discussion of strengths, weaknesses and potential future directions.
摘要
保持健康的房水流出（AHO）对于眼内细胞健康和稳定的视力非常重要。AHO 的损害可导致眼内压升高、视神经损伤和随之而来的青光眼。对 AHO 的深入了解将导致改进的青光眼手术，增强天然 AHO 并促进 AHO 靶向药物的开发。最近的 AHO 成像技术已经发展到可以实时评估，并侧重于 AHO 途径的结构评估和液体流动的功能记录。AHO 的结构评估主要由光相干断层扫描驱动，而流动的功能评估则使用各种方法进行，包括房水造影。本文回顾了 AHO 的结构和功能评估的进展，讨论了其优缺点和潜在的未来方向。
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