• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在植入假体组件后立即松开止血带可降低初次全膝关节置换术后深静脉血栓形成的发生率。

Release of the tourniquet immediately after the implantation of the components reduces the incidence of deep vein thrombosis after primary total knee arthroplasty.

作者信息

Zan P, Mol M O, Yao J J, Fan L, Yang D, Liu K, Li G

机构信息

Department of Orthopaedic Surgery, Tongji University, Shanghai Tenth People's Hospital, Zhabei Qu, Shanghai 200085, China.

Academic Medical Centre (AMC), University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam-Zuidoost, The Netherlands.

出版信息

Bone Joint Res. 2017 Sep;6(9):535-541. doi: 10.1302/2046-3758.69.BJR-2017-0149.R2.

DOI:10.1302/2046-3758.69.BJR-2017-0149.R2
PMID:28899856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5630995/
Abstract

AIMS

The length of the tourniquet time during total knee arthroplasty (TKA) is related to the incidence of post-operative deep vein thrombosis (DVT). Our aim in this study was to investigate the effect of the early release of the tourniquet on the incidence of DVT in patients undergoing TKA.

METHODS

A total of 200 patients who underwent TKA between November 2015 and November 2016 were prospectively enrolled. The tourniquet was inflated before surgery and released immediately after the introduction of the components (early release group). This group was compared with a retrospective cohort of 200 primary TKAs, in which the tourniquet was released after the dressings had been applied (late release group). The presence of a DVT was detected using bilateral lower limb ultrasonography. Peri-operative clinical and follow-up data were collected for analysis.

RESULTS

The incidence of DVT in the early release group (9 of 196, 4.6%) was significantly lower compared with the late release group (24 of 200, 12%; odds ratio (OR) 0.35, 95% confidence interval (CI) 0.16 to 0.78, p = 0.008). The incidence of proximal DVT in the early release group (1 of 196 (0.5%)) was significantly lower than in the late release group (8 of 196, 4%; OR 0.12, 95% CI 0.02 to 0.99, p = 0.020). Although the mean intra-operative blood loss was higher in the early release group, the mean post-operative drainage, total blood loss, transfusion requirements and complications were not significantly different in the two groups.

CONCLUSION

In patients who undergo TKA, releasing the tourniquet early is associated with a decreased incidence of DVT, without increasing the rate of complications.: 2017;6:535-541.

摘要

目的

全膝关节置换术(TKA)中止血带使用时间与术后深静脉血栓形成(DVT)的发生率相关。本研究旨在探讨在接受TKA的患者中早期松开止血带对DVT发生率的影响。

方法

前瞻性纳入2015年11月至2016年11月期间接受TKA的200例患者。手术前止血带充气,在植入假体组件后立即松开(早期松开组)。将该组与200例初次TKA的回顾性队列进行比较,后者在敷料应用后松开止血带(晚期松开组)。通过双侧下肢超声检查检测DVT的存在。收集围手术期临床和随访数据进行分析。

结果

早期松开组的DVT发生率(196例中的9例,4.6%)显著低于晚期松开组(200例中的24例,12%;优势比(OR)0.35,95%置信区间(CI)0.16至0.78,p = 0.008)。早期松开组近端DVT的发生率(196例中的1例(0.5%))显著低于晚期松开组(196例中的8例,4%;OR 0.12,95%CI 0.02至0.99,p = 0.020)。尽管早期松开组术中平均失血量较高,但两组术后平均引流量、总失血量、输血需求和并发症无显著差异。

结论

在接受TKA的患者中,早期松开止血带与DVT发生率降低相关,且不增加并发症发生率。: 2017;6:535 - 541。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd0/5630995/ac0abdd39a0d/bonejointres-06-535-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd0/5630995/ac0abdd39a0d/bonejointres-06-535-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd0/5630995/ac0abdd39a0d/bonejointres-06-535-g001.jpg

相似文献

1
Release of the tourniquet immediately after the implantation of the components reduces the incidence of deep vein thrombosis after primary total knee arthroplasty.在植入假体组件后立即松开止血带可降低初次全膝关节置换术后深静脉血栓形成的发生率。
Bone Joint Res. 2017 Sep;6(9):535-541. doi: 10.1302/2046-3758.69.BJR-2017-0149.R2.
2
Effect of tourniquet application on deep vein thrombosis after total knee arthroplasty.止血带应用对全膝关节置换术后深静脉血栓形成的影响。
Arch Orthop Trauma Surg. 2007 Oct;127(8):671-5. doi: 10.1007/s00402-006-0244-0. Epub 2006 Nov 11.
3
Tourniquet use in primary total knee arthroplasty is associated with a hypercoagulable status: a prospective thromboelastography trial.止血带在初次全膝关节置换术中的应用与高凝状态相关:一项前瞻性血栓弹力图试验。
Int Orthop. 2021 Dec;45(12):3091-3100. doi: 10.1007/s00264-021-05126-x. Epub 2021 Jun 30.
4
Effects of Tourniquet Release on Total Knee Arthroplasty.止血带松开对全膝关节置换术的影响。
Orthopedics. 2016 Jul 1;39(4):e642-50. doi: 10.3928/01477447-20160606-03. Epub 2016 Jun 13.
5
Use of a pneumatic tourniquet in total knee arthroplasty increases the risk of distal deep vein thrombosis: A prospective, randomized study.全膝关节置换术中使用气压止血带会增加远端深静脉血栓形成的风险:一项前瞻性随机研究。
Knee. 2016 Oct;23(5):887-9. doi: 10.1016/j.knee.2016.02.007. Epub 2016 Jun 29.
6
Does Tourniquet Use in TKA Affect Recovery of Lower Extremity Strength and Function? A Randomized Trial.全膝关节置换术中使用止血带会影响下肢力量和功能的恢复吗?一项随机试验。
Clin Orthop Relat Res. 2016 Jan;474(1):69-77. doi: 10.1007/s11999-015-4393-8.
7
Diabetes mellitus increases the incidence of deep vein thrombosis after total knee arthroplasty.糖尿病会增加全膝关节置换术后深静脉血栓形成的发生率。
Arch Orthop Trauma Surg. 2014 Jan;134(1):79-83. doi: 10.1007/s00402-013-1894-3. Epub 2013 Nov 26.
8
After early release of tourniquet in total knee arthroplasty, should it be reinflated or kept deflated? A randomized trial.在全膝关节置换术后早期松解止血带后,应重新充气还是保持放气状态?一项随机试验。
Knee Surg Sports Traumatol Arthrosc. 2017 Sep;25(9):2769-2777. doi: 10.1007/s00167-015-3710-9. Epub 2015 Jul 28.
9
Effects of Unilateral Tourniquet Used in Patients Undergoing Simultaneous Bilateral Total Knee Arthroplasty.单侧止血带在双侧同期全膝关节置换患者中的应用效果
Orthop Surg. 2017 May;9(2):180-185. doi: 10.1111/os.12329. Epub 2017 Jun 9.
10
[Safety and efficacy of rivaroxaban for prevention of deep vein thrombosis in patients with preoperative abnormal D-dimer after total knee arthroplasty].利伐沙班预防全膝关节置换术后术前D-二聚体异常患者深静脉血栓形成的安全性和有效性
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2014 Aug;28(8):955-9.

引用本文的文献

1
Management of Venous Thromboembolism After Hip and Knee Arthroplasty.髋关节和膝关节置换术后静脉血栓栓塞的管理
J Orthop Sports Med. 2025;7(3):311-327. doi: 10.26502/josm.511500210. Epub 2025 Jul 7.
2
Development and validation of a nomogram prediction model for perioperative deep vein thrombosis risk in arthroplasty: a retrospective study.关节置换术中围手术期深静脉血栓形成风险列线图预测模型的构建与验证:一项回顾性研究
Front Med (Lausanne). 2025 May 22;12:1528154. doi: 10.3389/fmed.2025.1528154. eCollection 2025.
3
No difference in reoperation rates or aseptic loosening following cemented total knee arthroplasty with or without a tourniquet.

本文引用的文献

1
The Incidence and Economic Burden of In-Hospital Venous Thromboembolism in the United States.美国住院患者静脉血栓栓塞症的发病率及经济负担
J Arthroplasty. 2017 Apr;32(4):1063-1066. doi: 10.1016/j.arth.2016.10.020. Epub 2016 Oct 21.
2
Prevalence of Venous Thromboembolic Events Is Low in Asians After Total Knee Arthroplasty Without Chemoprophylaxis.在未进行化学预防的亚洲人全膝关节置换术后,静脉血栓栓塞事件的发生率较低。
J Arthroplasty. 2017 Mar;32(3):974-979. doi: 10.1016/j.arth.2016.09.008. Epub 2016 Sep 28.
3
Incidence and risk factors of deep vein thrombosis (DVT) after total hip or knee arthroplasty: a retrospective study with routinely applied venography.
使用或不使用止血带进行骨水泥型全膝关节置换术后,再次手术率或无菌性松动方面无差异。
Arch Orthop Trauma Surg. 2025 May 24;145(1):313. doi: 10.1007/s00402-025-05933-6.
4
Weight-based tranexamic acid lowers the risk of postoperative blood loss and transfusion requirements compared with fixed-dose regimen in revision knee arthroplasty: a comparative study.在膝关节翻修手术中,与固定剂量方案相比,基于体重的氨甲环酸可降低术后失血风险和输血需求:一项比较研究。
J Orthop Traumatol. 2025 May 2;26(1):26. doi: 10.1186/s10195-025-00844-z.
5
Risk of deep vein thrombosis (DVT) in lower extremity after total knee arthroplasty (TKA) in patients over 60 years old.老年患者全膝关节置换术后下肢深静脉血栓形成(DVT)的风险。
J Orthop Surg Res. 2023 Nov 14;18(1):865. doi: 10.1186/s13018-023-04339-7.
6
Deep vein thrombosis and validation of the Caprini risk assessment model in Chinese orthopaedic trauma patients: a multi-center retrospective cohort study enrolling 34,893 patients.深静脉血栓形成和卡普兰风险评估模型在中国骨科创伤患者中的验证:一项多中心回顾性队列研究,纳入 34893 例患者。
Eur J Trauma Emerg Surg. 2023 Aug;49(4):1863-1871. doi: 10.1007/s00068-023-02265-1. Epub 2023 Apr 7.
7
An alternative method for personalized tourniquet pressure in total knee arthroplasty: a prospective randomized and controlled study.全膝关节置换术中个体化止血带压力的另一种方法:前瞻性随机对照研究。
Sci Rep. 2022 Jun 10;12(1):9652. doi: 10.1038/s41598-022-13672-6.
8
Impact of tourniquet during knee arthroplasty: a bayesian network meta-analysis of peri-operative outcomes.止血带在膝关节置换术中的影响:围手术期结局的贝叶斯网状荟萃分析。
Arch Orthop Trauma Surg. 2021 Jun;141(6):1007-1023. doi: 10.1007/s00402-020-03725-8. Epub 2021 Jan 8.
9
Venous thromboembolism in patients hospitalized for knee joint replacement surgery.膝关节置换术住院患者的静脉血栓栓塞症。
Sci Rep. 2020 Dec 31;10(1):22440. doi: 10.1038/s41598-020-79490-w.
10
Changes in perioperative hemoglobin and hematocrit in patients undergoing total knee arthroplasty: a prospective observational study of optimal timing of measurement.全膝关节置换术患者围手术期血红蛋白和血细胞比容的变化:测量最佳时机的前瞻性观察研究
J Int Med Res. 2020 Nov;48(11):300060520969303. doi: 10.1177/0300060520969303.
全髋关节或膝关节置换术后深静脉血栓形成(DVT)的发生率及危险因素:一项采用常规静脉造影的回顾性研究
Blood Coagul Fibrinolysis. 2017 Mar;28(2):126-133. doi: 10.1097/MBC.0000000000000556.
4
Use of a pneumatic tourniquet in total knee arthroplasty increases the risk of distal deep vein thrombosis: A prospective, randomized study.全膝关节置换术中使用气压止血带会增加远端深静脉血栓形成的风险:一项前瞻性随机研究。
Knee. 2016 Oct;23(5):887-9. doi: 10.1016/j.knee.2016.02.007. Epub 2016 Jun 29.
5
Obesity and Venous Thromboembolism in Total Knee Arthroplasty Patients in an Asian Population.亚洲人群全膝关节置换术患者的肥胖与静脉血栓栓塞
J Arthroplasty. 2016 Dec;31(12):2880-2883. doi: 10.1016/j.arth.2016.05.061. Epub 2016 Jun 4.
6
Balancing Thromboprophylaxis and Bleeding in Total Joint Arthroplasty: Impact of Eliminating Enoxaparin and Predonation and Implementing Pneumatic Compression and Tranexamic Acid.全关节置换术中血栓预防与出血的平衡:停用依诺肝素和术前采血并实施气压止血和氨甲环酸的影响
J Arthroplasty. 2016 Jun;31(6):1307-1312. doi: 10.1016/j.arth.2015.11.046. Epub 2015 Dec 17.
7
Intermittent pneumatic compression reduces the risk of deep vein thrombosis during post-operative lower limb immobilisation: a prospective randomised trial of acute ruptures of the Achilles tendon.间歇性充气加压可降低下肢术后制动期间深静脉血栓形成的风险:一项关于跟腱急性断裂的前瞻性随机试验。
Bone Joint J. 2015 May;97-B(5):675-80. doi: 10.1302/0301-620X.97B5.34581.
8
Tourniquet Release Prior to Dressing Application Reduces Blistering Following Total Knee Arthroplasty.包扎前松开止血带可减少全膝关节置换术后的水泡形成。
J Arthroplasty. 2015 Jul;30(7):1207-10. doi: 10.1016/j.arth.2015.02.035. Epub 2015 Feb 28.
9
Releasing of tourniquet before wound closure or not in total knee arthroplasty: a meta-analysis of randomized controlled trials.全膝关节置换术中伤口闭合前松开止血带与否:一项随机对照试验的荟萃分析
J Arthroplasty. 2015 Jan;30(1):31-7. doi: 10.1016/j.arth.2014.07.034. Epub 2014 Aug 7.
10
The influence of a half-course tourniquet strategy on peri-operative blood loss and early functional recovery in primary total knee arthroplasty.半程止血带策略对初次全膝关节置换术围手术期失血和早期功能恢复的影响。
Int Orthop. 2014 Feb;38(2):355-9. doi: 10.1007/s00264-013-2177-x. Epub 2013 Nov 21.