Zan P, Mol M O, Yao J J, Fan L, Yang D, Liu K, Li G
Department of Orthopaedic Surgery, Tongji University, Shanghai Tenth People's Hospital, Zhabei Qu, Shanghai 200085, China.
Academic Medical Centre (AMC), University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam-Zuidoost, The Netherlands.
Bone Joint Res. 2017 Sep;6(9):535-541. doi: 10.1302/2046-3758.69.BJR-2017-0149.R2.
The length of the tourniquet time during total knee arthroplasty (TKA) is related to the incidence of post-operative deep vein thrombosis (DVT). Our aim in this study was to investigate the effect of the early release of the tourniquet on the incidence of DVT in patients undergoing TKA.
A total of 200 patients who underwent TKA between November 2015 and November 2016 were prospectively enrolled. The tourniquet was inflated before surgery and released immediately after the introduction of the components (early release group). This group was compared with a retrospective cohort of 200 primary TKAs, in which the tourniquet was released after the dressings had been applied (late release group). The presence of a DVT was detected using bilateral lower limb ultrasonography. Peri-operative clinical and follow-up data were collected for analysis.
The incidence of DVT in the early release group (9 of 196, 4.6%) was significantly lower compared with the late release group (24 of 200, 12%; odds ratio (OR) 0.35, 95% confidence interval (CI) 0.16 to 0.78, p = 0.008). The incidence of proximal DVT in the early release group (1 of 196 (0.5%)) was significantly lower than in the late release group (8 of 196, 4%; OR 0.12, 95% CI 0.02 to 0.99, p = 0.020). Although the mean intra-operative blood loss was higher in the early release group, the mean post-operative drainage, total blood loss, transfusion requirements and complications were not significantly different in the two groups.
In patients who undergo TKA, releasing the tourniquet early is associated with a decreased incidence of DVT, without increasing the rate of complications.: 2017;6:535-541.
全膝关节置换术(TKA)中止血带使用时间与术后深静脉血栓形成(DVT)的发生率相关。本研究旨在探讨在接受TKA的患者中早期松开止血带对DVT发生率的影响。
前瞻性纳入2015年11月至2016年11月期间接受TKA的200例患者。手术前止血带充气,在植入假体组件后立即松开(早期松开组)。将该组与200例初次TKA的回顾性队列进行比较,后者在敷料应用后松开止血带(晚期松开组)。通过双侧下肢超声检查检测DVT的存在。收集围手术期临床和随访数据进行分析。
早期松开组的DVT发生率(196例中的9例,4.6%)显著低于晚期松开组(200例中的24例,12%;优势比(OR)0.35,95%置信区间(CI)0.16至0.78,p = 0.008)。早期松开组近端DVT的发生率(196例中的1例(0.5%))显著低于晚期松开组(196例中的8例,4%;OR 0.12,95%CI 0.02至0.99,p = 0.020)。尽管早期松开组术中平均失血量较高,但两组术后平均引流量、总失血量、输血需求和并发症无显著差异。
在接受TKA的患者中,早期松开止血带与DVT发生率降低相关,且不增加并发症发生率。: 2017;6:535 - 541。