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肝淀粉样变性:一种能伪装并欺骗我们认知的病症!

Hepatic Amyloidosis: Something That Can camouflage and Deceive our Perception!

作者信息

Nair Anirudh V, Yadav Manish Kumar, Unni Madhavan N, Simi C M, Biji K A, Manoj K S, Ali Shabeer, Nair Ajith K

机构信息

Department of Radiodiagnosis and Interventional Radiology, Kerala Institute of Medical Science and Research Centre, Trivandrum, Kerala, India.

Department of Pathology, Kerala Institute of Medical Science and Research Centre, Trivandrum, Kerala, India.

出版信息

Indian J Med Paediatr Oncol. 2017 Apr-Jun;38(2):236-239. doi: 10.4103/ijmpo.ijmpo_46_16.

Abstract

Amyloidosis is a multi-systemic diffusely infiltrating disease due to extracellular deposition of protein-mucopolysaccharide complexes. The type of protein deposited determines the subgroup of amyloid. Hepatic amyloidosis is a rare infiltrating disease affecting the hepatic parenchyma. A wide range of clinical presentation and atypical imaging findings delay the diagnosis of amyloidosis, while tissue biopsy demonstrating amyloid deposits is vital for a definitive diagnosis.

摘要

淀粉样变性是一种多系统弥漫性浸润性疾病,由蛋白质 - 粘多糖复合物的细胞外沉积引起。沉积的蛋白质类型决定了淀粉样蛋白的亚组。肝淀粉样变性是一种罕见的浸润性疾病,累及肝实质。广泛的临床表现和不典型的影像学表现会延迟淀粉样变性的诊断,而组织活检显示淀粉样蛋白沉积对于明确诊断至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8435/5582570/5cfb3e406c1e/IJMPO-38-236-g001.jpg

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