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与链球菌性蜂窝织炎相关的类过敏性紫癜:一例报告及文献综述

Anaphylactoid Purpura Associated with Streptococcal Cellulitis: A Case Report and Literature Review.

作者信息

Saito Yuko, Ookawara Susumu, Uchima Hisataka, Ishida Takeshi, Kakei Masafumi, Sugawara Hitoshi

机构信息

Division of General Medicine, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama-City, Saitama-ken 330-8503, Japan.

Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama-City, Saitama-ken 330-8503, Japan.

出版信息

Case Rep Med. 2017;2017:5960898. doi: 10.1155/2017/5960898. Epub 2017 Aug 16.

DOI:10.1155/2017/5960898
PMID:28900445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5576416/
Abstract

A 54-year-old Japanese man noticed painful swelling and redness of his left leg. He was admitted for treatment of cellulitis, which was accompanied with increased anti-streptolysin O and anti-streptokinase titers in his clinical course. After Piperacillin/Tazobactam administration, the skin lesion resolved. However, the patient then developed arthritis, palpable purpura, and intermittent abdominal pain, later found to be secondary to a severe duodenal ulcer. He was diagnosed with cellulitis-associated anaphylactoid purpura and was given prednisolone, which dramatically improved his symptoms. The anaphylactoid purpura was likely caused by -induced cellulitis, which was successfully treated with prednisolone. Association between these diseases is rare.

摘要

一名54岁的日本男性注意到左腿出现疼痛性肿胀和发红。他因蜂窝织炎入院治疗,在其临床过程中伴有抗链球菌溶血素O和抗链激酶滴度升高。给予哌拉西林/他唑巴坦治疗后,皮肤病变消退。然而,患者随后出现关节炎、可触及的紫癜和间歇性腹痛,后来发现是由严重十二指肠溃疡继发引起的。他被诊断为蜂窝织炎相关性类过敏性紫癜,并给予泼尼松龙治疗,症状得到显著改善。类过敏性紫癜可能是由诱导性蜂窝织炎引起的,泼尼松龙成功治疗了该疾病。这些疾病之间的关联很少见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6b/5576416/a1e0b5e04afc/CRIM2017-5960898.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6b/5576416/7ea35c43c17a/CRIM2017-5960898.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6b/5576416/765c53b6ad3a/CRIM2017-5960898.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6b/5576416/a1e0b5e04afc/CRIM2017-5960898.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6b/5576416/7ea35c43c17a/CRIM2017-5960898.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6b/5576416/765c53b6ad3a/CRIM2017-5960898.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6b/5576416/a1e0b5e04afc/CRIM2017-5960898.003.jpg

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本文引用的文献

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Anaphylactoid purpura triggered by cellulitis as a favorable prognosis: case report and literature review.蜂窝织炎引发的类过敏性紫癜预后良好:病例报告及文献综述
Springerplus. 2016 Jul 19;5(1):1112. doi: 10.1186/s40064-016-2792-2. eCollection 2016.
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Alcohol Use As a Risk Factor in Infections and Healing: A Clinician's Perspective.饮酒作为感染与愈合中的一个风险因素:临床医生视角
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Histopathology and correlates of systemic disease in adult Henoch-Schönlein purpura: a retrospective study of microscopic and clinical findings in 68 patients at Mayo Clinic.成人过敏性紫癜的组织病理学和系统性疾病相关性:梅奥诊所 68 例患者的微观和临床发现的回顾性研究。
J Am Acad Dermatol. 2013 Mar;68(3):420-424.e3. doi: 10.1016/j.jaad.2012.08.011. Epub 2012 Sep 6.
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Piperacillin/tazobactam--induced petechial rash.
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