Nakaseko Haruna, Uemura Osamu, Nagai Takuhito, Yamakawa Satoshi, Hibi Yoshiko, Yamasaki Yasuhito, Yamamoto Masaki
Department of Pediatric Nephrology, Aichi Children's Health and Medical Center, 1-2 Osakada Myoken-Cho, Obu, Aichi 474-8710, Japan.
Int J Pediatr. 2011;2011:562638. doi: 10.1155/2011/562638. Epub 2011 Oct 2.
We evaluated the prevalence and the types of infectious foci in oral as well as ear, nose, and throat diseases, and we examined incidence of renal involvement with active treatment for focal infection in children with Henoch-Schönlein Purpura. A total of 96 children who presented at Aichi Children's Health and Medical Center and were diagnosed as having HSP were evaluated for infectious foci in the ear, nose, throat, and oral cavities. Seventy-one of 96 children (74.0%) had some type of infectious lesion, such as sinusitis or tonsillitis, and the prevalence of sinusitis was the highest (51 cases, 53.7%). In 44 HSP patients without renal involvement at the first examination, the incidence of nephritis was lower (13.6%) than in previous reports (17-54%) due to our aggressive intervention for infectious foci.
我们评估了口腔以及耳鼻喉疾病中感染灶的患病率和类型，并研究了在对过敏性紫癜患儿的局灶性感染进行积极治疗时肾脏受累的发生率。共有96名在爱知县儿童健康与医疗中心就诊并被诊断为患有过敏性紫癜的儿童接受了耳鼻喉和口腔感染灶的评估。96名儿童中有71名（74.0%）患有某种类型的感染性病变，如鼻窦炎或扁桃体炎，其中鼻窦炎的患病率最高（51例，53.7%）。在首次检查时无肾脏受累的44例过敏性紫癜患者中，由于我们对感染灶采取了积极干预措施，肾炎的发生率（13.6%）低于以往报告（17%-54%）。
