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超声检查和计算机断层扫描在评估喉癌和下咽癌中甲状腺软骨侵犯情况的有效性

Effectiveness of ultrasonography and computed tomography in assessing thyroid cartilage invasion in laryngeal and hypopharyngeal cancers.

作者信息

Dhoot Nilu Malpani, Choudhury B, Kataki A C, Kakoti L, Ahmed S, Sharma J

机构信息

Department of Radiology, Dr. B. Borooah Cancer Institute, Star Telecom, 2nd Floor, B.R. Arcade, Opp Hotel Priya Palace, Janpath, Ulubari, Guwahati, Assam 781007 India.

Department of pathology, Dr. B. Borooah Cancer Institute, Star Telecom, 2nd Floor, B.R. Arcade, Opp Hotel Priya Palace, Janpath, Ulubari, Guwahati, Assam 781007 India.

出版信息

J Ultrasound. 2017 Aug 19;20(3):205-211. doi: 10.1007/s40477-017-0259-0. eCollection 2017 Sep.

Abstract

OBJECTIVE

To evaluate the adequacy of ultrasonography (US) and computed tomography (CT) in the assessment of thyroid cartilage invasion in patients with airway cancer.

MATERIALS AND METHODS

Sixty-two consecutive patients referred to our institute underwent US and CT to stage laryngeal ( = 27) or hypopharyngeal ( = 35) cancer in this prospective study. Two radiologists, who were blinded to the patients' clinical histories and histopathology, evaluated thyroid cartilage invasion on US and CT separately and independently. Fifty-eight of the 64 patients (90%) underwent surgery. The histopathologic findings were used as the standard of reference for comparison and statistical analysis.

RESULTS

For thyroid cartilage invasion, the detection rate on CT and US was 98%. CT achieved a sensitivity of 91% and a specificity of 75%, while US attained a sensitivity of 98% and a specificity of 75%. The difference between CT and US in terms of sensitivity was not statistically significant.

CONCLUSION

US and CT have high diagnostic performance in evaluating thyroid cartilage invasion. US is more sensitive than CT in diagnosing invasion of the thyroid cartilage; however, the difference is not statistically significant. US can be used to solve the diagnostic dilemma of the presence or absence of cartilage invasion when CT is inconclusive, as CT is more widely used in staging laryngeal and hypopharyngeal cancers.

摘要

目的

评估超声(US)和计算机断层扫描(CT)在评估气道癌患者甲状腺软骨侵犯情况时的充分性。

材料与方法

在这项前瞻性研究中,62例连续转诊至我院的患者接受了US和CT检查,以对喉癌(n = 27)或下咽癌(n = 35)进行分期。两名对患者临床病史和组织病理学不知情的放射科医生分别独立评估US和CT上的甲状腺软骨侵犯情况。64例患者中有58例(90%)接受了手术。组织病理学结果用作比较和统计分析的参考标准。

结果

对于甲状腺软骨侵犯,CT和US的检出率均为98%。CT的敏感性为91%,特异性为75%,而US的敏感性为98%,特异性为75%。CT和US在敏感性方面的差异无统计学意义。

结论

US和CT在评估甲状腺软骨侵犯方面具有较高的诊断性能。在诊断甲状腺软骨侵犯方面,US比CT更敏感;然而,差异无统计学意义。当CT结果不明确时,由于CT在喉癌和下咽癌分期中应用更广泛,US可用于解决软骨侵犯与否的诊断难题。

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