Otolaryngology Unit, Department of BMS, Neuroscience and Sensory Organs, University of Bari "Aldo Moro", Bari, Italy.
Otolaryngology Unit, "Di Venere" Hospital, Bari, Italy.
Am J Otolaryngol. 2021 Jan-Feb;42(1):102772. doi: 10.1016/j.amjoto.2020.102772. Epub 2020 Oct 20.
With the current COVID-19 outbreak, otolaryngologists are most exposed to the risk of infection due to the nature of the specialty.This is why they are required to find safer diagnostic alternatives minimizing aerosol-generating procedures. The aim of this study is to explore the accuracy of transcutaneous laryngeal ultrasonography (TLUSG) in order to assess vocal fold movement.
We performed blindly both TLUSG and flexible fiberoptic laryngoscopy(FFL) on 38 patients, from March to June 2020. Patients were divided into two groups:the former with normally mobile vocal folds and the latter with unilateral vocal fold paralysis.
On FFL findings, 10/38 patients (26,31%) had unilateral vocal fold paralysis; on TLUSG results, 9/38 patients (23.68%) presented impaired vocal fold motion. In comparison to laryngoscopy, the sensitivity, specificity, positive predictive value and negative predictive value of TLUSG for assessment of vocal fold mobility was 80%, 96.42%, 88.88%, 93.10% respectively. A significant association between the two techniques was found on the Chi-square test: X = 19.7722 (p value <0.00001). Cohen's K value showed a substantial agreement: K = 0,79.
Although TLUSG could undoubtedly not replace laringoscopy, it represents a noninvasive and useful diagnostic tool for otolaryngologists especially during covid-19 pandemic.Data collected about its high sensitivity and specificity suggest that TLUSG could be a reliable method to screen vocal fold paralysis without performing aerosol-generating procedures, thus providing clear visualization of laryngeal real-time movements, even in non-compliant or high-risk infection patients. Our results allow us to consider TLUSG as part of the preoperative assessment of vocal folds in patients undergoing thyroidectomy.
由于耳鼻喉科的专业性质,耳鼻喉科医生在当前的 COVID-19 疫情中面临最大的感染风险。这就是为什么他们需要找到更安全的替代诊断方法,尽量减少产生气溶胶的程序。本研究旨在探讨经皮喉超声检查(TLUSG)评估声带运动的准确性。
我们于 2020 年 3 月至 6 月对 38 例患者进行了 TLUSG 和纤维喉镜(FFL)盲法检查。患者分为两组:一组为声带活动正常,另一组为单侧声带麻痹。
FFL 检查发现 38 例患者中有 10 例(26.31%)单侧声带麻痹;TLUSG 检查结果显示 9 例(23.68%)声带运动受限。与喉镜相比,TLUSG 评估声带活动度的敏感性、特异性、阳性预测值和阴性预测值分别为 80%、96.42%、88.88%、93.10%。卡方检验显示两种技术之间存在显著相关性:X=19.7722(p 值<0.00001)。Cohen's K 值显示存在较强的一致性:K=0.79。
尽管 TLUSG 无疑不能替代喉镜,但它是耳鼻喉科医生的一种非侵入性且有用的诊断工具,特别是在 COVID-19 大流行期间。关于其高敏感性和特异性的数据表明,TLUSG 可以作为一种无需产生气溶胶的程序筛查声带麻痹的可靠方法,从而提供实时喉部运动的清晰可视化,即使在不配合或高感染风险的患者中也是如此。我们的研究结果表明,TLUSG 可以作为甲状腺切除术患者声带术前评估的一部分。