He Lan-Juan, Zhu Xiang-Dong
Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China.
Zhongguo Zhong Yao Za Zhi. 2016 Jun;41(12):2344-2349. doi: 10.4268/cjcmm20161228.
To analyze the regularities of prescriptions in "a guide to clinical practice with medical record" (Ye Tianshi) for diarrhoea based on traditional Chinese medicine inheritance support system(V2.5), and provide a reference for further research and development of new traditional Chinese medicines in treating diarrhoea. Traditional Chinese medicine inheritance support system was used to build a prescription database of Chinese medicines for diarrhoea. The software integration data mining method was used to analyze the prescriptions according to "four natures", "five flavors" and "meridians" in the database and achieve frequency statistics, syndrome distribution, prescription regularity and new prescription analysis. An analysis on 94 prescriptions for diarrhoea was used to determine the frequencies of medicines in prescriptions, commonly used medicine pairs and combinations, and achieve 13 new prescriptions. This study indicated that the prescriptions for diarrhoea in "a guide to clinical practice with medical record" are mostly of eliminating dampness and tonifying deficienccy, with neutral drug property, sweet, bitter or hot in flavor, and reflecting the treatment principle of "activating spleen-energy and resolving dampness".
基于中医传承辅助系统（V2.5）分析《临证指南医案》（叶天士）中腹泻的用药规律，为腹泻治疗新中药的进一步研发提供参考。运用中医传承辅助系统建立腹泻中药方剂数据库，采用软件集成数据挖掘方法，依据数据库中药物的“四气”“五味”“归经”对处方进行分析，实现频次统计、证候分布、用药规律及新方分析。对94首腹泻方剂进行分析，确定了方剂中药物的频次、常用药对及组合，并得出13首新方。本研究表明，《临证指南医案》中腹泻方剂多为祛湿补虚之剂，药性平和，味多甘、苦、辛，体现了“健脾化湿”的治疗原则。
