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主动脉缩窄和室间隔缺损的一期修复:手术策略与资源利用的比较

Single-Stage Repair of Coarctation of the Aorta and Ventricular Septal Defect: A Comparison of Surgical Strategies and Resource Utilization.

作者信息

Callahan Connor, Saudek David, Shillingford Amanda, Creighton Sara, Hill Garick, Johnson William, Tweddell James S, Mitchell Michael E, Woods Ronald K

机构信息

1 Division of Pediatric Cardiothoracic Surgery, Department of Surgery, Children's Hospital of Wisconsin, Milwaukee, WI, USA.

2 Division of Cardiology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.

出版信息

World J Pediatr Congenit Heart Surg. 2017 Sep;8(5):559-563. doi: 10.1177/2150135117727256.

Abstract

BACKGROUND

We sought to compare clinical outcomes and resource utilization for two surgical approaches for single-stage repair of coarctation of the aorta and ventricular septal defect (VSD).

METHODS

This was a retrospective chart review of 21 consecutive neonates and infants undergoing single-stage repair of coarctation of the aorta and VSD. Group 1 included 13 patients with both arch repair and VSD repair completed via sternotomy. Group 2 included eight patients with off-pump arch repair via left thoracotomy followed by repositioning and VSD repair via sternotomy. Primary clinical outcome was arch reintervention. Secondary outcomes included various measures of resource utilization.

RESULTS

Group 1 patients demonstrated younger age at repair (median of 10 days vs 57 days for group 2; P = .05) and lower proximal arch z scores (-4.2 vs -2.3 for group 2; P = .003). Arch reintervention occurred in 0 of 8 patients in group 2 and 1 (7.7%) of 13 patients in group 1 ( P = nonsignificant). Group 2 was associated with lower total charges (US$68,301 vs US$211,723 for group 1; P = .0007), shorter length of stay (8 days vs 23 days for group 1; P = .004), and shorter duration of postoperative mechanical ventilation (0.5 days vs 4.0 days for group 1; P = .0008). Group 2 was also associated with shorter total cardiopulmonary bypass time (86 minutes vs 201 minutes for group 1; P = .0009).

CONCLUSION

Single-stage two-incision repair of coarctation and VSD in appropriately selected patients may be associated with higher value of care. Confirmation of this finding will require further study based on larger numbers of patients.

摘要

背景

我们试图比较两种手术方法用于主动脉缩窄和室间隔缺损(VSD)一期修复的临床结果和资源利用情况。

方法

这是一项对21例连续接受主动脉缩窄和VSD一期修复的新生儿和婴儿进行的回顾性图表审查。第1组包括13例通过胸骨切开术完成主动脉弓修复和VSD修复的患者。第2组包括8例通过左胸切口进行非体外循环主动脉弓修复,随后通过胸骨切开术重新定位并进行VSD修复的患者。主要临床结果是主动脉弓再次干预。次要结果包括各种资源利用指标。

结果

第1组患者修复时年龄较小(中位数为10天,而第2组为57天;P = 0.05),近端主动脉弓z值较低(第2组为-2.3,第1组为-4.2;P = 0.003)。第2组8例患者中0例发生主动脉弓再次干预,第1组13例患者中有1例(7.7%)发生(P = 无显著性差异)。第2组的总费用较低(第1组为211,723美元,第2组为68,301美元;P = 0.0007),住院时间较短(第1组为23天,第2组为8天;P = 0.004),术后机械通气时间较短(第1组为4.0天,第2组为0.5天;P = 0.0008)。第2组还与较短的总体外循环时间相关(第1组为201分钟,第2组为86分钟;P = 0.0009)。

结论

在适当选择的患者中,主动脉缩窄和VSD的一期双切口修复可能与更高的医疗价值相关。这一发现的确认需要基于更多患者的进一步研究。

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