丙泊酚抗癌特性的新发现。
Novel Findings of Anti-cancer Property of Propofol.
作者信息
Wang Jiaqiang, Cheng Chien-Shan, Lu Yan, Ding Xiaowei, Zhu Minmin, Miao Changhong, Chen Jiawei
机构信息
Department of Anesthesiology, Fudan University Shanghai Cancer Center, No. 270 DongAn Road, Shanghai 200032, China.
Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, China.
出版信息
Anticancer Agents Med Chem. 2018;18(2):156-165. doi: 10.2174/1871520617666170912120327.
BACKGROUND
Propofol, a widely used intravenous anesthetic agent, is traditionally applied for sedation and general anesthesia. Explanation: Recent attention has been drawn to explore the effect and mechanisms of propofol against cancer progression in vitro and in vivo. Specifically, the proliferation-inhibiting and apoptosis-inducing properties of propofol in cancer have been studied. However, the underlying mechanisms remain unclear.
CONCLUSION
This review focused on the findings within the past ten years and aimed to provide a general overview of propofol's malignance-modulating properties and the potential molecular mechanisms.
背景
丙泊酚是一种广泛使用的静脉麻醉剂，传统上用于镇静和全身麻醉。解释：最近，人们开始关注探索丙泊酚在体外和体内对抗癌症进展的作用及机制。具体而言，已经研究了丙泊酚在癌症中的增殖抑制和凋亡诱导特性。然而，其潜在机制仍不清楚。
结论
本综述聚焦于过去十年的研究结果，旨在全面概述丙泊酚的恶性调节特性及其潜在的分子机制。
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