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2010 - 2015年埃塞俄比亚亚的斯亚贝巴四家政府医院急诊科中孕妇及其他非孕妇的急性中毒情况

Acute poisonings during pregnancy and in other non-pregnant women in emergency departments of four government hospitals, Addis Ababa, Ethiopia: 2010-2015.

作者信息

Eyasu Mebrahtu, Dida Tolesa, Worku Yoseph, Worku Solomon, Shafie Mensur

机构信息

Department of Pharmacology, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Department of Nursing, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

出版信息

Trop Med Int Health. 2017 Oct;22(10):1350-1360. doi: 10.1111/tmi.12940. Epub 2017 Sep 13.

Abstract

OBJECTIVE

To characterise acute poisonings in pregnant and non-pregnant women treated at emergency departments of government hospitals in Addis Ababa, Ethiopia, between 2010 and 2015.

METHODS

All data for acutely poisoned women were retrospectively collected from patient medical charts at the emergency departments of Saint Paul's Hospital Millennium Medical College, Ras Desta Memorial Hospital, Yekatit 12 Hospital Medical College and Zewditu Memorial Hospital. Data were collected by extraction questionnaire and analysed using SPSSv. 20 statistical software.

RESULTS

During the study period, 998 cases of acutely poisoned women were listed in the hospital registries. Of these, complete data for inclusion in the study were available for 592. 36.3% of the study participants were in the age group of 20-24, with a mean (±SD) age of 23.03 (±6.3) years. 80.9% were from Addis Ababa; 4.6% were pregnant. The mean arrival time of all cases was 4.14 h. 85.5% of all study cases were due to intentional self-poisoning, of whom 42.1% were discharged without complications. The most common poisons were bleach and organophosphates; 25.9% of pregnant cases and 32.6% of non-pregnant cases were poisoned by bleach; and 18.5% of pregnant cases and 18.9% of non-pregnant cases had organophosphate poisoning. 0.7% had a history of poisoning; all were non-pregnant women. The common route of poison exposure was oral, and the case fatality rate of organophosphate poisoning in pregnant and non-pregnant women was 20 and 1.87%, respectively. The pre-hospital intervention for the majority of the women was milk, in 12.0% of cases.

CONCLUSION

Acute poisoning remains a public health problem in our community. Bleach is the most common poisons. Our present findings indicate the necessity of educational programmes on preventable reasons of acute poisonings and their outcomes on pregnant and non-pregnant women.

摘要

目的

对2010年至2015年期间在埃塞俄比亚亚的斯亚贝巴政府医院急诊科接受治疗的孕妇和非孕妇急性中毒情况进行特征描述。

方法

从圣保罗医院千禧医学院、拉斯·德斯塔纪念医院、耶卡蒂特12医院医学院和泽韦迪图纪念医院急诊科的患者病历中回顾性收集所有急性中毒女性的数据。通过提取问卷收集数据,并使用SPSSv. 20统计软件进行分析。

结果

在研究期间,医院登记了998例急性中毒女性病例。其中,有592例可获得纳入研究的完整数据。36.3%的研究参与者年龄在20 - 24岁之间,平均(±标准差)年龄为23.03(±6.3)岁。80.9%来自亚的斯亚贝巴;4.6%为孕妇。所有病例的平均到达时间为4.14小时。85.5%的研究病例是故意自我中毒,其中42.1%无并发症出院。最常见的毒物是漂白剂和有机磷;25.9%的孕妇病例和32.6%的非孕妇病例因漂白剂中毒;18.5%的孕妇病例和18.9%的非孕妇病例有机磷中毒。0.7%有中毒史;均为非孕妇。毒物暴露的常见途径是口服,孕妇和非孕妇有机磷中毒的病死率分别为20%和1.87%。大多数女性的院前干预措施是服用牛奶,占12.0%的病例。

结论

急性中毒仍是我们社区的一个公共卫生问题。漂白剂是最常见的毒物。我们目前的研究结果表明,有必要开展关于急性中毒可预防原因及其对孕妇和非孕妇影响的教育项目。

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