Department of Biological and Medical Sciences, Oxford Brookes University, Headington Campus, Oxford OX3 0BP, UK
Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Open Biol. 2017 Sep;7(9). doi: 10.1098/rsob.170165.
The shape and form of protozoan parasites are inextricably linked to their pathogenicity. The evolutionary pressure associated with establishing and maintaining an infection and transmission to vector or host has shaped parasite morphology. However, there is not a 'one size fits all' morphological solution to these different pressures, and parasites exhibit a range of different morphologies, reflecting the diversity of their complex life cycles. In this review, we will focus on the shape and form of spp., a group of very successful protozoan parasites that cause a range of diseases from self-healing cutaneous leishmaniasis to visceral leishmaniasis, which is fatal if left untreated.
原生动物寄生虫的形态与其致病性密切相关。与建立和维持感染以及传播给媒介或宿主相关的进化压力塑造了寄生虫的形态。然而，对于这些不同的压力，并没有一种“一刀切”的形态解决方案，寄生虫表现出一系列不同的形态，反映了它们复杂生命周期的多样性。在这篇综述中，我们将重点介绍 spp.的形状和形态，这是一组非常成功的原生动物寄生虫，它们会引起一系列疾病，从自限性皮肤利什曼病到内脏利什曼病，如果不治疗，内脏利什曼病是致命的。
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