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季节性情感障碍和非季节性情感障碍:荷兰精神障碍队列研究(NESDA)的结果

Seasonal affective disorder and non-seasonal affective disorders: results from the NESDA study.

作者信息

Winthorst Wim H, Roest Annelieke M, Bos Elisabeth H, Meesters Ybe, Penninx Brenda W J H, Nolen Willem A, de Jonge Peter

机构信息

, MD, Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

, PhD, Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

出版信息

BJPsych Open. 2017 Aug 30;3(4):196-203. doi: 10.1192/bjpo.bp.116.004960. eCollection 2017 Jul.

Abstract

BACKGROUND

Seasonal affective disorder (SAD) is considered to be a subtype of depression.

AIMS

To compare the clinical picture of SAD to non-seasonal affective disorders (non-SADs).

METHOD

Diagnoses according to the (DSM-IV) were established in 2185 participants of the Netherlands Study of Depression and Anxiety. The Seasonal Pattern Assessment Questionnaire was administered to diagnose SAD. Symptoms of depression and anxiety were measured with the Inventory of Depressive Symptoms, the Beck Anxiety Inventory and the Fear Questionnaire.

RESULTS

Participants with SAD, participants with a lifetime bipolar disorder and participants with a lifetime comorbid anxiety and depressive disorder scored highest in terms of psychopathology in the past year. The seasonal distribution of major depressive episodes was not different for participants with or without SAD.

CONCLUSIONS

SAD may be a measure of severity of depression with a subjectively perceived worsening of symptoms in the winter months.

DECLARATION OF INTEREST

Y.M. has received research funding and served as a consultant for Royal Philips Electronics NV and The Litebook Company Ltd. W.A.N. has received grants from the Netherlands Organization for Health Research and Development, the European Union, the Stanley Medical Research Institute, Astra Zeneca, Eli Lilly, GlaxoSmithKline and Wyeth; has received honoraria/speaker's fees from Astra Zeneca, Pfizer, Servier and Wyeth; and has served in advisory boards for Astra Zeneca, Pfizer and Servier.

COPYRIGHT AND USAGE

© The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license.

摘要

背景

季节性情感障碍(SAD)被认为是抑郁症的一种亚型。

目的

比较季节性情感障碍与非季节性情感障碍(非SAD)的临床表现。

方法

在荷兰抑郁与焦虑研究的2185名参与者中,依据《精神疾病诊断与统计手册》第四版(DSM-IV)进行诊断。采用季节性模式评估问卷来诊断季节性情感障碍。使用抑郁症状量表、贝克焦虑量表和恐惧问卷来测量抑郁和焦虑症状。

结果

患有季节性情感障碍的参与者、患有终生双相情感障碍的参与者以及患有终生共病焦虑和抑郁障碍的参与者在过去一年的精神病理学方面得分最高。无论是否患有季节性情感障碍,参与者的重度抑郁发作的季节性分布并无差异。

结论

季节性情感障碍可能是抑郁症严重程度的一种衡量指标,其症状在冬季会主观上感觉加重。

利益声明

Y.M. 已获得研究资金,并担任皇家飞利浦电子公司和Litebook有限公司的顾问。W.A.N. 已获得荷兰卫生研究与发展组织、欧盟、斯坦利医学研究所、阿斯利康、礼来、葛兰素史克和惠氏的资助;已从阿斯利康、辉瑞、施维雅和惠氏获得酬金/演讲费;并曾在阿斯利康、辉瑞和施维雅的顾问委员会任职。

版权与使用

© 皇家精神科医学院2017年。这是一篇开放获取文章,根据知识共享非商业性、无衍生作品(CC BY-NC-ND)许可协议分发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aaf/5572284/bda60e1fc24f/bjporcpsych004960-g001.jpg

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