Ibrahim Mohammed, Gilbert Kissan
Department of Surgical Oncology, Shifa Hospitals, Tirunelveli, India.
HCG Kauvery Cancer Centre, Chennai, India.
Transl Gastroenterol Hepatol. 2017 Aug 9;2:64. doi: 10.21037/tgh.2017.07.02. eCollection 2017.
Adenocarcinoma stands the most common malignancies in the gastric carcinomas and holds a significant mortality and morbidity rates annually, due to the early vague symptoms among the population and hence the delayed presentation at advanced stages of cancer. In India the screening programs for gastric cancer has been a setback due to various logistics reasons and the data available from reporting is also not content. Our study is a review article featuring the management of gastric cancer in the Indian population. The lifestyle of India population is varied right from its southern region to its northern counterparts, which is due to its diversified culture within the country. Studies have concluded that the northern population tends to have a higher incidence comparatively and the various risk factors associated with the disease has been discussed. Management of the gastric cancer in India remains the same compared to the outside world, though the availability of endoscopic ultrasound and other technical advancements remain sparse in the field of diagnostics and staging of the disease. D2 gastrectomy remains the mainstay of surgery among the Indian population though significant number of patients are deemed inoperable on table. Neo adjuvant Chemotherapy, Radiotherapy and Targeted therapy is yet to be efficiently used across the country according to our study as there is lack of data in our registries. The incidence is decreasing in developing nations and more proximal cancers are reported. However, in India the major population-based cancer registries report an incidence decline only in Mumbai and Chennai. A shift from distal to proximal as the site of disease has not been reported from India. The contribution of the Indian scientific fraternity to the world medical literature for gastric cancer is sparse and it is clear that a lot more is to be done; the possible reason may be a busy clinical schedule or lack of initiatives. There is an urgent need for research in various aspects of gastric cancer from India including epidemiological and therapeutic areas.
腺癌是胃癌中最常见的恶性肿瘤,由于人群早期症状模糊,导致癌症晚期就诊延迟,每年的死亡率和发病率都很高。在印度,由于各种后勤原因,胃癌筛查项目受挫,报告中的可用数据也不完善。我们的研究是一篇综述文章,介绍了印度人群中胃癌的管理情况。印度人群的生活方式从南部地区到北部地区各不相同,这是由于该国文化的多样性。研究得出结论,北方人群的发病率相对较高,并讨论了与该疾病相关的各种风险因素。与世界其他地区相比,印度胃癌的管理方式仍然相同,尽管在该疾病的诊断和分期领域,内镜超声和其他技术进步的应用仍然很少。D2胃切除术仍然是印度人群手术的主要方式,尽管相当数量的患者在手术台上被认为无法手术。根据我们的研究,新辅助化疗、放疗和靶向治疗在全国尚未得到有效应用,因为我们的登记处缺乏相关数据。在发展中国家,发病率正在下降,报告的近端癌症更多。然而,在印度,主要的基于人群的癌症登记处报告仅孟买和钦奈的发病率有所下降。印度尚未报告疾病部位从远端向近端的转变。印度科学界对世界胃癌医学文献的贡献很少,显然还有很多工作要做;可能的原因可能是临床日程繁忙或缺乏主动性。印度迫切需要在胃癌的各个方面进行研究,包括流行病学和治疗领域。