Grotemeyer K H, Husstedt I W, Schlake H P
Klinik und Poliklinik für Neurologie der Universität Münster.
Dtsch Med Wochenschr. 1987 Nov 6;112(45):1740-3. doi: 10.1055/s-2008-1068322.
Vasomotor headaches are commonly, especially in the international literature, classified under ordinary migraine. Since beta-blockers seem to be the drug of choice in the prevention of migraine, 30 patients were given placebo and three times 40 mg propranolol in a double-blind cross-over trial. Among 24 fully assessable sets of tests only four showed a decrease in the frequency of headaches by more than 50%. In three patients the frequency actually increased over the placebo effect.
血管舒缩性头痛通常,尤其是在国际文献中,被归类为普通偏头痛。由于β受体阻滞剂似乎是预防偏头痛的首选药物,在一项双盲交叉试验中,对30名患者给予了安慰剂以及三次每次40毫克的普萘洛尔。在24组可完全评估的测试中,只有4组显示头痛频率降低超过50%。在3名患者中,头痛频率实际上比安慰剂效应时有所增加。