Yonekura S, Nagao T, Komatsuda M, Arimori S
Fourth Department of Internal Medicine, School of Medicine, Tokai University, Isehara, Japan.
Eur J Haematol. 1987 Sep;39(3):233-6. doi: 10.1111/j.1600-0609.1987.tb00763.x.
A female patient who had been initially diagnosed with non-Hodgkin's lymphoma (NHL) and achieved complete clinical remission with combined chemotherapy, developed overt adult T-cell leukemia (ATL) after 9 yr of disease-free survival. This is the first case of the development of ATL following the complete remission of NHL. Secondary malignant neoplasms are not well-documented in patients previously diagnosed with Hodgkin's disease. Although there have been a few reports concerning the occurrence of secondary malignancy in patients with non-Hodgkin's lymphoma (NHL), there has never been a documented case of ATL following long-term survival from NHL. Here, we report a case of typical adult T-cell leukemia (ATL) which occurred after 9 yr disease-free survival from NHL.
一名最初被诊断为非霍奇金淋巴瘤（NHL）并通过联合化疗实现完全临床缓解的女性患者，在无病生存9年后发展为明显的成人T细胞白血病（ATL）。这是NHL完全缓解后发生ATL的首例病例。继发性恶性肿瘤在先前诊断为霍奇金病的患者中记录并不充分。虽然有一些关于非霍奇金淋巴瘤（NHL）患者发生继发性恶性肿瘤的报道，但从未有过NHL长期生存后发生ATL的记录病例。在此，我们报告一例典型的成人T细胞白血病（ATL），其发生在NHL无病生存9年后。
