Mercuri Santo R, Gregorio Greta, Brianti Pina
Unit of Dermatology and Cosmetology, IRCCS University Vita-Salute San Raffaele, Milan, Italy.
Private Practitioner, Milan, Italy.
G Ital Dermatol Venereol. 2017 Oct;152(5):424-431. doi: 10.23736/S0392-0488.17.05658-9.
Psoriasis is an inflammatory disease with a chronic course; often it is associated with various serious comorbidity and a compromised quality of life. Psoriasis patients experience a low self-esteem, feelings of shame and frustration, they report a seriously compromised social and sentimental sphere, difficulties at work and in daily activities, coming in most serious cases to suicidal ideation.
Our job is to experiment the introduction of the innovative PSOdisk tool to quantify the impact of psoriasis on quality of life, comparing it with PASI Index. We presented the empirical analysis, gathered through a sample of 24 patients, followed for 6 months of therapy with biologics. Patients were encountered three times, at a distance of three months each, during which we calculated a PASI score and we administered the PSOdisk.
Through various statistical analyses we have identified a relationship between PSOdisk value and other parameters such as patient age and particular locations of psoriasis. Specifically we systematically observed that patients aged less than 50 years reported a more compromised quality of life (QoL) when compared to older patients with the same clinical severity. At the same time patients with hands or genitals involvement show higher values associated with the PSOdisk compared with patients without such anatomical deficiency.
PSOdisk instrument proved to be effective and optimal for widespread distribution in the outpatient activity. It also encourages dialogue between doctor and patient; it increases compliance of the latter with regard to the therapy and a desirable improvement in outcomes. A systematic assessment of the impact of psoriasis on patients' QoL is fundamental and must complement the objective assessment in clinical practice.
银屑病是一种病程慢性的炎症性疾病；它常与各种严重的合并症相关，且生活质量受损。银屑病患者自尊心较低，有羞耻和挫败感，他们报告社交和情感领域严重受损，工作及日常活动存在困难，在最严重的情况下会出现自杀念头。
我们的工作是试验引入创新的PSOdisk工具来量化银屑病对生活质量的影响，并将其与银屑病面积和严重程度指数（PASI）进行比较。我们展示了通过24名患者样本收集的实证分析结果，这些患者接受了6个月的生物制剂治疗。患者在三个月的间隔期内接受了三次随访，在此期间我们计算了PASI评分并使用了PSOdisk。
通过各种统计分析，我们确定了PSOdisk值与其他参数（如患者年龄和银屑病的特定部位）之间的关系。具体而言，我们系统地观察到，与临床严重程度相同的老年患者相比，年龄小于50岁的患者报告的生活质量受损程度更高。同时，手部或生殖器受累的患者与无此类解剖学缺陷的患者相比，PSOdisk相关值更高。
PSOdisk工具被证明在门诊活动中广泛应用是有效且最佳的。它还促进了医患之间的对话；提高了患者对治疗的依从性，并使治疗结果得到理想改善。对银屑病对患者生活质量影响的系统评估至关重要，且必须在临床实践中补充客观评估。
