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二极管激光治疗口腔小型血管畸形:一项前瞻性病例系列研究。

Diode laser to treat small oral vascular malformations: A prospective case series study.

作者信息

Bacci Christian, Sacchetto Luca, Zanette Gastone, Sivolella Stefano

机构信息

Department of Neurosciences, Dentistry Section, University of Padova, Via Giustiniani 2, 35131 Padova, Italy.

出版信息

Lasers Surg Med. 2018 Feb;50(2):111-116. doi: 10.1002/lsm.22737. Epub 2017 Sep 14.

Abstract

OBJECTIVE

The current work examined a consecutive series of patients presenting vascular malformations (VMs) and venous lakes (VLs) of the lip and oral mucosa who were treated with transmucosal diode laser applications and assessed over a 1 year period.

STUDY DESIGN AND METHODS

Fifty-nine patients (31 males and 28 females) presenting low-flow VMs or VLs of the oral cavity were treated transmucosally using a diode laser (with an 830 nm operating wavelength and 1.6 W output power) with a 320 µm diameter flexible fiber. All the lesions were assessed 7 days, 30 days, and 1 year after the laser treatment, and the lesion reduction percentage was scored on a one to five scale. The patients were also asked to assess their pain perception daily during the 7 days following the treatment using a visual analog scale (VAS).

RESULTS

There were no procedure-related intra- or post-operative complications; only modest pain intensity was reported. Thirty days after the treatment, lesion reduction was described as excellent or good in 52 cases; it was fair or poor in 7. Six patients (F:M ratio 2:4) required a second diode laser application. At the 1 year follow-up, volume reduction was complete in 48 out of 59 patients; there were five recurrences (F:M ratio 3:2). No relevant gender-related differences were noted.

CONCLUSION

The use of diode laser application to treat small oral VMs and VLs was associated to shorter operating times and fewer postoperative complications with respect to the scapel surgery approach. More than one session may nevertheless be required if the anomaly is larger than 10 mm. Lasers Surg. Med. 50:111-116, 2018. © 2017 Wiley Periodicals, Inc.

摘要

目的

本研究连续观察了一系列接受经黏膜二极管激光治疗的唇部和口腔黏膜血管畸形(VMs)及静脉湖(VLs)患者,并在1年期间对其进行评估。

研究设计与方法

59例口腔低流量VMs或VLs患者(31例男性,28例女性)接受经黏膜二极管激光治疗,使用直径320μm的柔性光纤,二极管激光工作波长830nm,输出功率1.6W。在激光治疗后7天、30天和1年对所有病变进行评估,病变缩小百分比按1至5分进行评分。还要求患者在治疗后的7天内每天使用视觉模拟量表(VAS)评估疼痛感受。

结果

未出现与手术相关的术中或术后并发症;仅报告有轻微疼痛。治疗30天后,52例病变缩小情况被描述为优秀或良好;7例为中等或较差。6例患者(女性与男性比例为2:4)需要再次进行二极管激光治疗。在1年随访时,59例患者中有48例体积缩小完全;有5例复发(女性与男性比例为3:2)。未发现明显的性别差异。

结论

与手术刀手术方法相比,使用二极管激光治疗口腔小VMs和VLs的手术时间更短,术后并发症更少。然而,如果病变大于10mm,可能需要不止一次治疗。《激光外科与医学》50:111 - 116, 2018。© 2017威利期刊公司

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