a Universidade do Estado do Rio de Janeiro, Hospital Universitário Pedro Ernesto , Rio de Janeiro , Brazil.
b Universidade do Estado do Rio de Janeiro, Faculdade de Ciências Médicas, Programa de Pós-Graduação em Ciências Médicas , Rio de Janeiro , Brazil.
J Am Coll Nutr. 2017 Nov-Dec;36(8):624-630. doi: 10.1080/07315724.2017.1338631. Epub 2017 Sep 14.
C-reactive protein is an acute-phase protein that has been found in association with adiposity and cardiovascular disease risk. In this paper, the objective was to assess the relationship of C-reactive protein to four anthropometric measurements: body mass index, waist-to-height ratio, C index, and waist circumference.
A cross-sectional random sample of the Study of Cardiovascular Risk in Adolescents (Portuguese acronym "ERICA") was included in the study. The analysis was adjusted for the complex sampling design. Poisson regression models with robust variance were used to estimate a multivariate-adjusted prevalence rate ratio expressing the relationship of each anthropometric measure to C-reactive protein. We evaluated adolescents aged 12 to 17 years participating in the capital of Porto Alegre, Brazil.
In all, 778 adolescents were included (60% female, 58% aged 15-17 years). Waist-to-height ratio was found to be the strongest adiposity marker associated with C-reactive protein even after adjusting for age, sex, smoking, physical activity, and insulin resistance (prevalence rate ratio = 7.09; 95% confidence interval, 5.01-9.18; p < 0.001).
Waist-to-height ratio is a strong predictor of C-reactive protein in adolescents in Porto Alegre, Brazil.
C 反应蛋白是一种急性期蛋白，与肥胖和心血管疾病风险有关。本文旨在评估 C 反应蛋白与四种人体测量学指标（体重指数、腰高比、C 指数和腰围）之间的关系。
本研究纳入了青少年心血管风险研究（葡萄牙语缩写为“ERICA”）的一个横断面随机样本。分析采用了复杂抽样设计的校正。使用具有稳健方差的泊松回归模型来估计多元调整后患病率比，以表达每个人体测量指标与 C 反应蛋白的关系。我们评估了巴西阿雷格里港首都的 12 至 17 岁青少年。
共纳入 778 名青少年（60%为女性，58%年龄为 15-17 岁）。即使在调整了年龄、性别、吸烟、体力活动和胰岛素抵抗等因素后，腰高比仍然是与 C 反应蛋白相关性最强的肥胖标志物（患病率比=7.09；95%置信区间，5.01-9.18；p<0.001）。
在巴西阿雷格里港，腰高比是青少年 C 反应蛋白的一个强有力的预测指标。
