a Clinica Oculistica, Di.N.O.G.M.I , University of Genova , Genova , Italy.
b U.O.C. Clinica Oculistica , Ospedale Policlinico San Martino , Genova , Italy.
Ocul Immunol Inflamm. 2019;27(2):266-275. doi: 10.1080/09273948.2017.1341988. Epub 2017 Sep 14.
Dry eye disease (DED) is a multifactorial disease that results in symptoms of discomfort, visual disturbance, and damage to the ocular surface. Because chronic inflammation plays an important role in DED, treatment with topical corticosteroids has been demonstrated to ameliorate the signs and symptoms of the disease. Although these agents have proven short-term efficacy, their long-term use may cause intraocular pressure elevation and cataract progression. A carefully review of the different studies shows that differences between corticosteroids may exist regarding the incidence of side effects and evidence of efficacy in DED patients.
干眼症（DED）是一种多因素疾病，可导致不适症状、视觉障碍和眼表损伤。由于慢性炎症在 DED 中起着重要作用，因此局部皮质类固醇的治疗已被证明可改善疾病的体征和症状。尽管这些药物具有短期疗效，但长期使用可能会导致眼压升高和白内障进展。对不同研究的仔细回顾表明，皮质类固醇之间可能存在差异，表现在不良反应发生率和 DED 患者疗效证据方面。
