Pockett S, Philip B A
Department of Physiology, University of Auckland, New Zealand.
Neurosci Lett. 1987 Oct 5;80(3):347-50. doi: 10.1016/0304-3940(87)90480-0.
Stages in the return of the toe-spreading reflex after sciatic nerve injury were examined using the rat. It was found that the earliest stages in the return of the reflex do not indicate nerve regeneration, but rather reflect the development of adrenalin sensitivity in denervated muscles. Probably systemic adrenalin released during the reflex-testing procedure causes muscle contractions which imitate a nerve-induced toe-spread reflex.
利用大鼠研究了坐骨神经损伤后足趾伸展反射恢复的阶段。发现反射恢复的最早阶段并不表明神经再生,而是反映了失神经肌肉中肾上腺素敏感性的发展。可能在反射测试过程中释放的全身性肾上腺素会引起肌肉收缩,从而模拟神经诱导的足趾伸展反射。