Leng Gillian, Partridge Gemma
National Institute for Health and Care Excellence, London, UK.
Heart. 2018 Jan;104(1):10-15. doi: 10.1136/heartjnl-2016-311028. Epub 2017 Sep 14.
The National Institute for Health and Care Excellence (NICE) was established in 1999 to provide evidence-based guidance. The task of producing guidance by reviewing primary research data and using an advisory committee to develop evidence-based recommendations, is not straightforward. Guidance production is, however, less challenging than the task of putting evidence-based recommendations into practice.NICE is very sensitive to this challenge as, since 1999, over 1500 pieces of NICE guidance have been published. A number of pieces of guidance relate to heart disease, including pharmaceutical agents, new medical technologies and clinical guidelines. Examples include guidelines on acute heart failure and atrial fibrillation, and advice on technologies including edoxaban and implantable cardioverter defibrillators.The research evidence is clear that a change in practice rarely comes about as a result of simply disseminating guidance on best practice. Simple dissemination is particularly ineffective if the guidance has not been produced by a well-respected, credible organisation. It is also clear from the literature that implementation is more successful when more than one approach is taken, and when there is alignment between efforts at organisational, local and national levels.At an organisational level, there should be support from the Board for quality improvement, with ongoing measurement of progress. Resources should be provided for targeted change programmes, particularly where new guidance suggests improvements are required. A systematic process for putting change in place should include identifying barriers to change, agreeing interventions to overcome the barriers and drive forward improvement and planning for implementation and evaluation.
英国国家卫生与临床优化研究所(NICE)成立于1999年,旨在提供循证指南。通过审查原始研究数据并利用咨询委员会制定循证建议来生成指南的任务并非易事。然而,生成指南的挑战性低于将循证建议付诸实践的任务。NICE对这一挑战非常敏感,自1999年以来,已发布了1500多条NICE指南。许多指南涉及心脏病,包括药物制剂、新医疗技术和临床指南。例如,关于急性心力衰竭和心房颤动的指南,以及关于依度沙班和植入式心脏复律除颤器等技术的建议。研究证据清楚表明,实践中的改变很少仅仅是由于简单地传播最佳实践指南而产生的。如果指南不是由备受尊敬、可信的组织制定的,简单传播尤其无效。从文献中也可以清楚地看出,当采用多种方法并且组织、地方和国家层面的努力保持一致时,实施会更成功。在组织层面,董事会应支持质量改进,并持续衡量进展情况。应为有针对性的变革计划提供资源,特别是在新指南表明需要改进的情况下。实施变革的系统流程应包括识别变革的障碍、商定克服障碍并推动改进的干预措施,以及规划实施和评估。