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在人类胃肠道中大量定殖。

abundant colonization in human gastrointestinal tract.

作者信息

Wu Feifan, Guo Xianfeng, Zhang Jiachun, Zhang Min, Ou Zihao, Peng Yongzheng

机构信息

Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Shenzhen, Guangdong 510282, P.R. China.

Department of Laboratory Medicine, Changsha Medical University, Shenzhen, Guangdong 510282, P.R. China.

出版信息

Exp Ther Med. 2017 Oct;14(4):3122-3126. doi: 10.3892/etm.2017.4878. Epub 2017 Aug 3.

Abstract

can produce short-chain fatty acids, including acetate and propionate, and can be associated with the metabolic state and mood of the host. The present study investigated the colonization characteristics of in healthy individuals <1-80 years old in Southern China. A total of 150 fresh fecal samples were collected, and bacterial DNA was isolated from these samples for quantitative polymerase chain reaction analysis. demonstrated a high colonization rate and abundant colonization in the human gastrointestinal tract. The colonization rate varied between 43.33-93.33%, and the abundance of ranged between 3.22-5.76 log cells g-1 (<1 years old) and 3.06-9.33 log cells g-1 (>1 year old). The permillage of in total bacteria ranged between 0.004-1.479. There was presence of -like bacteria in younger individuals with a gradual increase in the number of bacteria maintained at a high level with increasing ages (between 1 and 60 years old), but with a decrease in elderly individuals (>60 years old). The results of the present study demonstrated that is abundantly colonized in the human gastrointestinal tract.

摘要

可产生短链脂肪酸,包括乙酸盐和丙酸盐,并可能与宿主的代谢状态和情绪有关。本研究调查了华南地区1至80岁健康个体中[细菌名称未给出]的定植特征。共收集了150份新鲜粪便样本,并从这些样本中分离出细菌DNA用于定量聚合酶链反应分析。[细菌名称未给出]在人类胃肠道中显示出高定植率和丰富的定植情况。定植率在43.33%至93.33%之间变化,[细菌名称未给出]的丰度在3.22至5.76 log细胞/克(<1岁)和3.06至9.33 log细胞/克(>1岁)之间。[细菌名称未给出]在总细菌中的千分比在0.004至1.479之间。在较年轻个体中存在[细菌名称未给出]样细菌,随着年龄增长(1至60岁之间)细菌数量逐渐增加并维持在较高水平,但在老年个体(>60岁)中数量减少。本研究结果表明,[细菌名称未给出]在人类胃肠道中大量定植。

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