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原发性子宫神经外胚层肿瘤：两例病例报告。

Primitive uterine neuroectodermal tumours: Two case reports.

作者信息

Eskiyörük İpek, Küçükgöz Güleç Ümran, Paydaş Semra, Güzel Ahmet Barış, Vardar Mehmet Ali, Bağır Emine

机构信息

Çukurova University Faculty of Medicine, Department of Obstetrics and Gyneacology, Adana, Turkey.

Çukurova University Faculty of Medicine, Department of Medical Oncology, Adana, Turkey.

出版信息

Turk J Obstet Gynecol. 2015 Sep;12(3):185-187. doi: 10.4274/tjod.58295. Epub 2015 Sep 15.

DOI:10.4274/tjod.58295
PMID:28913066
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5558395/
Abstract

Primitive neuroectodermal tumor (PNET) arise from Kulchitsky cells and are rarely seen in the female genital tract. Differential diagnosis of PNET can be made based on immunohistochemical profiles and genetic analyses. Genital tract pNETs are very aggressive pathologies with different clinical and molecular manifestations and there are no standard guidelines for treatment. We aimed to present two cases of uterine PNETs with different symptomatology and clinical findings.

摘要

原始神经外胚层肿瘤（PNET）起源于库尔契茨基细胞，在女性生殖道中很少见。PNET的鉴别诊断可基于免疫组织化学特征和基因分析。生殖道原始神经外胚层肿瘤是具有不同临床和分子表现的侵袭性很强的病变，且尚无标准的治疗指南。我们旨在介绍两例具有不同症状和临床发现的子宫原始神经外胚层肿瘤病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3927/5558395/ed02e0fbd302/TJOD-12-185-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3927/5558395/1012522f65ea/TJOD-12-185-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3927/5558395/ed02e0fbd302/TJOD-12-185-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3927/5558395/1012522f65ea/TJOD-12-185-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3927/5558395/ed02e0fbd302/TJOD-12-185-g2.jpg

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本文引用的文献

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Primary primitive neuroectodermal tumor of the uterus: a case report with an unusual molecular pathology finding.
J Cancer Res Ther. 2011 Oct-Dec;7(4):488-90. doi: 10.4103/0973-1482.92010.
2
Ewing sarcoma-primitive neuroectodermal tumor of the uterus: a clinicopathologic, immunohistochemical and ultrastructural study of one case.子宫尤文肉瘤-原始神经外胚层肿瘤：1 例临床病理、免疫组化和超微结构研究。
Arch Gynecol Obstet. 2011 May;283(5):1139-43. doi: 10.1007/s00404-010-1557-3. Epub 2010 Jun 30.
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Endometrial endometrioid adenocarcinoma associated with primitive neuroectodermal tumour of the uterus: a poor prognostic subtype of uterine tumours.子宫内膜样腺癌伴子宫原始神经外胚层肿瘤：一种预后不良的子宫肿瘤亚型。
子宫原始神经外胚层肿瘤：多模式治疗方法后的良好临床反应。
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Uterine primitive neuroectodermal tumor: a case report.子宫原始神经外胚层肿瘤：一例报告
Arch Gynecol Obstet. 2009 Feb;279(2):259-61. doi: 10.1007/s00404-008-0699-z. Epub 2008 Jun 4.
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Primitive neuroectodermal tumor of the uterus: a case report and review of literature.子宫原始神经外胚层肿瘤：一例报告并文献复习
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