Selçuk Selçuk, Küçükbaş Mehmet, Yenidede Lter, Kayataş Eser Semra, Eser Ahmet, Çam Çetin, Kutlu Hüseyin Tayfun
Zeynep Kamil Women and Children's Diseases Education and Research Hospital, Clinics of Obstetrics and Gynecology, İstanbul, Turkey.
Fatih Sultan Mehmet Training and Research Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey.
Turk J Obstet Gynecol. 2016 Mar;13(1):7-10. doi: 10.4274/tjod.88786. Epub 2016 Mar 10.
The aim of the present study was to evaluate the pregnancy rates of intrauterine insemination (IUI) and controlled ovarian hyperstimulation (COH) in patients with one-sided tubal occlusion on hysterosalpingography (HSG).
Patients who underwent COH/IUI were enrolled into this retrospective cohort study. The patients with one-sided tubal occlusion diagnosed under HSG who met the inclusion criteria were accepted into the study group. The control group consisted of patients with unexplained infertility. The outcomes of COH/IUI were compared between the study and control groups.
Ninety-seven patients in the study group (n=44) and control group (n=53) who underwent COH/IUI treatment were included into study. The biochemical, clinical, and ongoing pregnancy rates were similar between patients with unilateral occlusion diagnosed under HSG and those with unexplained infertility. The spontaneous pregnancy rate within one year was higher in patients with normal HSG than in patients with unilateral tubal occlusion, but the difference did not show statistical significance.
Infertile patients with one-sided tubal occlusion in HSG can be managed as with patients with unexplained infertility and normal HSG findings. In addition, COH/IUI may be considered as the first-line treatment option in the management of these patients.
本研究旨在评估子宫输卵管造影（HSG）显示单侧输卵管阻塞患者的宫内人工授精（IUI）和控制性卵巢过度刺激（COH）的妊娠率。
接受COH/IUI治疗的患者纳入本回顾性队列研究。HSG诊断为单侧输卵管阻塞且符合纳入标准的患者被纳入研究组。对照组由不明原因不孕症患者组成。比较研究组和对照组COH/IUI的治疗结果。
97例接受COH/IUI治疗的患者纳入研究，其中研究组44例，对照组53例。HSG诊断为单侧阻塞的患者与不明原因不孕症患者的生化妊娠率、临床妊娠率和持续妊娠率相似。HSG正常的患者一年内自然妊娠率高于单侧输卵管阻塞患者，但差异无统计学意义。
HSG显示单侧输卵管阻塞的不孕症患者可按不明原因不孕症且HSG结果正常的患者进行处理。此外，COH/IUI可被视为这些患者治疗的一线选择。
