Kınay Tuğba, Öztürk Başarır Zehra, Fırtına Tuncer Serap, Akpınar Funda, Kayıkçıoğlu Fulya, Koç Sevgi
Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Clinic of Obstetrics and Gynecology, Ankara, Turkey.
Zekai Tahir Burak Women's Health Training and Research Hospital, Clinic of Obstetrics and Gynecology, Ankara, Turkey.
Turk J Obstet Gynecol. 2016 Mar;13(1):31-36. doi: 10.4274/tjod.36043. Epub 2016 Mar 10.
The aim of the study was to investigate the prevalence of endometrial polyps in patients with uterine fibroids and associated factors of coexistence of these two pathologies.
The medical records of 772 patients who underwent hysterectomy because of uterine fibroids were retrospectively reviewed. Patients were divided into two groups according to the presence of endometrial polyps in the histopathologic examination. Demographic, clinical and histopathologic findings of the patients with and without endometrial polyps were compared. Student's t-test, Mann-Whitney U test, Pearson's Chi-square test, and logistic regression analysis were used for statistical analysis.
The prevalence of the endometrial polyps in uterine fibroid cases was found 20.1% (n=155). Age ≥45 years (odds ratio [OR] 1.61; 95% confidence interval [CI]: [1.06-2.44]; p=0.014), presence of hypertension (23.9% vs. 17.5%; p=0.047), endometrial hyperplasia (OR 4.00; 95% CI: [1.92-8.33]; p<0.001) and cervical polyps (OR 3.13; 95% CI: [1.69-5.88]; p<0.001) were significantly associated with the coexistence of endometrial polyps and uterine fibroids. Endometrial polyps were more common in patients with ≥2 fibroids (p=0.023) and largest fibroid <8 cm (p=0.009). A negative correlation was found between condom use and endometrial polyps (8.1% vs. 3.9%; p=0.044).
The prevalence of the endometrial polyps coexisting with uterine fibroids was 20.1%. Age, hypertension, endometrial hyperplasia, cervical polyps, and number of fibroids were positively correlated; condom use and size of largest fibroid were negatively correlated with the coexistence of these two pathologies.
本研究旨在调查子宫肌瘤患者中子宫内膜息肉的患病率以及这两种病理情况共存的相关因素。
回顾性分析772例因子宫肌瘤接受子宫切除术患者的病历。根据组织病理学检查中是否存在子宫内膜息肉将患者分为两组。比较有和没有子宫内膜息肉患者的人口统计学、临床和组织病理学结果。采用学生t检验、曼-惠特尼U检验、皮尔逊卡方检验和逻辑回归分析进行统计分析。
子宫肌瘤病例中子宫内膜息肉的患病率为20.1%（n = 155）。年龄≥45岁（比值比[OR] 1.61；95%置信区间[CI]：[1.06 - 2.44]；p = 0.014）、患有高血压（23.9%对17.5%；p = 0.047）、子宫内膜增生（OR 4.00；9
