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脉搏波形血流动力学监测设备:心脏手术患者目标导向治疗的最新进展及应用

Pulse waveform hemodynamic monitoring devices: recent advances and the place in goal-directed therapy in cardiac surgical patients.

作者信息

Hendy Adham, Bubenek Şerban

机构信息

Carol Davila University of Medicine and Pharmacy, Bucharest, 1 Department of Cardiovascular Anaesthesia and Intensive Care, C.C. Iliescu Emergency Institute for Cardiovascular Diseases, Bucharest, Romania.

出版信息

Rom J Anaesth Intensive Care. 2016 Apr;23(1):55-65. doi: 10.21454/rjaic.7518.231.wvf.

Abstract

Hemodynamic monitoring has evolved and improved greatly during the past decades as the medical approach has shifted from a static to a functional approach. The technological advances have led to innovating calibrated or not, but minimally invasive and noninvasive devices based on arterial pressure waveform (APW) analysis. This systematic clinical review outlines the physiologic rationale behind these recent technologies. We describe the strengths and the limitations of each method in terms of accuracy and precision of measuring the flow parameters (stroke volume, cardiac output) and dynamic parameters which predict the fluid responsiveness. We also analyzed the place of the APW monitoring devices in goal-directed therapy (GDT) protocols in cardiac surgical patients. According to the data from the three GDT-randomized control trials performed in cardiac surgery (using two types of APW techniques PiCCO and FloTrac/Vigileo), these devices did not demonstrate that they played a role in decreasing mortality, but only decreasing the ventilation time and the ICU and hospital length of stay.

摘要

在过去几十年中,随着医学方法从静态方法转变为功能方法,血流动力学监测有了很大的发展和改进。技术进步催生了基于动脉压力波形(APW)分析的创新型设备,这些设备有的经过校准,有的则没有,但都是微创和无创的。本系统临床综述概述了这些最新技术背后的生理原理。我们从测量血流参数(每搏量、心输出量)和预测液体反应性的动态参数的准确性和精确性方面,描述了每种方法的优点和局限性。我们还分析了APW监测设备在心脏手术患者目标导向治疗(GDT)方案中的地位。根据在心脏手术中进行的三项GDT随机对照试验(使用两种APW技术PiCCO和FloTrac/Vigileo)的数据,这些设备并未证明它们在降低死亡率方面发挥了作用,而只是缩短了通气时间以及重症监护病房(ICU)和医院的住院时间。

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