Young Natharnia, Atan Ixora Kamisan, Rojas Rodrigo Guzman, Dietz Hans Peter
Department of Gynaecology, Monash Health, Melbourne, Australia.
Department of Obstetrics & Gynaecology, Monash Health, 823-865 Centre Road, Bentleigh East, VIC, Australia.
Int Urogynecol J. 2018 Aug;29(8):1129-1134. doi: 10.1007/s00192-017-3455-8. Epub 2017 Sep 15.
The objective was to determine the association between body mass index (BMI) and symptoms and signs of female pelvic organ prolapse (POP).
An observational cross-sectional study of 964 archived datasets of women seen for symptoms and signs of lower urinary tract and pelvic organ dysfunction between September 2011 and February 2014 at a tertiary urogynaecology centre in Australia was carried out. An in-house standardised interview, the International Continence Society Pelvic Organ Prolapse Quantification (ICS POP-Q) and 4-D translabial ultrasound, followed by analysis of ultrasound volumes for pelvic organ descent and hiatal area on Valsalva, were performed, blinded against other data.
There is a positive association between BMI and posterior compartment prolapse on clinical examination and ultrasound imaging, but not for the anterior and central compartments. There was no association with prolapse symptom bother and a negative association with symptoms of prolapse.
In this observational study, we found a strong association between all tested measures of posterior compartment descent and BMI, both clinical and on imaging.
目的是确定体重指数（BMI）与女性盆腔器官脱垂（POP）的症状及体征之间的关联。
对2011年9月至2014年2月期间在澳大利亚一家三级泌尿妇科中心因下尿路及盆腔器官功能障碍症状和体征就诊的964名女性的存档数据集进行了一项观察性横断面研究。进行了一项内部标准化访谈、国际尿控协会盆腔器官脱垂定量（ICS POP-Q）和经阴唇4D超声检查，随后对盆腔器官下降的超声容积以及Valsalva动作时的裂孔面积进行分析，对其他数据进行盲法处理。
在临床检查和超声成像中，BMI与后盆腔脱垂呈正相关，但前盆腔和中盆腔无此关联。与脱垂症状困扰无关联，与脱垂症状呈负相关。
在这项观察性研究中，我们发现后盆腔下降的所有测试指标与BMI之间存在密切关联，无论是临床还是影像学方面。
