Melmed S, Rushakoff R J
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California.
Endocrinol Metab Clin North Am. 1987 Sep;16(3):805-21.
The pathophysiology and diagnosis of ectopic hormone syndromes are discussed, and a classification of hypothalamic and pituitary ectopic syndromes is provided. Ectopic hypothalamic syndromes resulting from tumor elaboration of GRH, GnRH, CRF, and SRIF and ectopic pituitary hormone hypersecretion of GH, PRL, and TSH are reviewed comprehensively. A practical approach to the clinical work-up and management of these newly described disorders is provided.
本文讨论了异位激素综合征的病理生理学和诊断，并给出了下丘脑和垂体异位综合征的分类。全面回顾了由肿瘤分泌生长激素释放激素（GRH）、促性腺激素释放激素（GnRH）、促肾上腺皮质激素释放因子（CRF）和生长抑素（SRIF）引起的异位下丘脑综合征，以及生长激素（GH）、催乳素（PRL）和促甲状腺激素（TSH）的异位垂体激素分泌过多情况。提供了针对这些新描述疾病的临床检查和管理的实用方法。
