Department of Neonatology, Özel Ortadoğu Hastanesi, Ankara, Turkey.
Department of Ophthalmology, Ankara Training and Research Hospital, Ankara, Turkey.
J Chin Med Assoc. 2017 Nov;80(11):729-732. doi: 10.1016/j.jcma.2017.08.003. Epub 2017 Sep 14.
To evaluate the ocular findings in children between 3 and 5 years of age who had received phototherapy in the neonatal period and to investigate whether they had phototherapy-related permanent ocular damage clinically.
The phototherapy group (n = 57) consisted of children who had undergone phototherapy for at least 24 h, and the control group (n = 43) comprised children who had not received phototherapy. Ophthalmic examinations consisted of assessment of visual acuity, convergence near point, ocular movements, ocular alignment, dynamic retinoscopy, cycloplegic refraction and biomicroscopic examination of anterior segment and posterior segment (using a 90 D lens in the latest).
All children were orthophoric and had normal eye movements. A significant difference was found between the phototherapy group and control group regarding convergence near point 3.0 (2.0-5.0) vs 3.0 (2.0-5.0) (p = 0.018), right cycloplegic spherical equivalent 1.0 (0.0-3.0) vs 0.75 (0.0-4.75) (p = 0.011) and left cycloplegic spherical equivalent 1.0 (0.075-3.0) vs 0.75 (0.0-5.25) (p = 0.006).The study groups were similar according to cycloplegic spherical and cylindrical refractions. However, no significant difference was found between the groups regarding the need for eye glasses.
Although there were significant differences between the phototherapy and the control groups according to the convergence near point and right and the left eye cycloplegic spherical equivalent, the similarity between the groups regarding the need for eyeglasses suggested that difference was clinically insignificant.
评估在新生儿期接受过光疗的 3 至 5 岁儿童的眼部发现,并研究他们是否存在临床上与光疗相关的永久性眼部损害。
光疗组(n=57)包括接受至少 24 小时光疗的儿童,对照组(n=43)包括未接受光疗的儿童。眼科检查包括视力、集合近点、眼球运动、眼球对齐、动态视网膜检查、睫状肌麻痹验光以及前段和后段的生物显微镜检查(最近使用 90 D 透镜)。
所有儿童均为正位,眼球运动正常。光疗组与对照组在集合近点 3.0(2.0-5.0)与 3.0(2.0-5.0)(p=0.018)、右眼睫状肌麻痹球镜等效值 1.0(0.0-3.0)与 0.75(0.0-4.75)(p=0.011)和左眼睫状肌麻痹球镜等效值 1.0(0.075-3.0)与 0.75(0.0-5.25)(p=0.006)方面存在显著差异。尽管两组在睫状肌麻痹球镜和圆柱镜屈光度方面相似,但在需要戴眼镜方面,两组无显著差异。
尽管根据集合近点和右眼及左眼睫状肌麻痹球镜等效值,光疗组与对照组之间存在显著差异,但在需要戴眼镜方面两组的相似性表明这种差异在临床上无意义。