Shi Wenyin, Nichols Romaine C, Flampouri Stella, Li Zuofeng, Hsi Wen, Huh Soon, Ho Meng Wei, Henderson Randall H, Mendenhall Nancy P, Hoppe Bradford S
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USAUniversity of Florida, Proton Therapy Institute, Jacksonville, FL, USA.
Thorac Cancer. 2013 May;4(2):198-202. doi: 10.1111/j.1759-7714.2012.00141.x.
In this case report, we present the history and treatment of a 70-year-old man with synchronous bilateral non-small-cell lung cancers with proton-beam radiation. Surgical treatment was not feasible and optimized photon intensity-modulated radiotherapy (IMRT) to the primary tumors would have resulted in unacceptably high normal-tissue exposures. Proton-beam radiation enabled radiation dose escalation and concurrent chemotherapy while maintaining normal-tissue tolerance.
在本病例报告中，我们介绍了一名70岁男性同步双侧非小细胞肺癌接受质子束放疗的病史及治疗情况。手术治疗不可行，对原发性肿瘤采用优化的光子调强放射治疗（IMRT）会导致正常组织受照剂量高得难以接受。质子束放疗在维持正常组织耐受性的同时，能够提高放射剂量并同步进行化疗。
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