Hu Tian-Yuan, Gao Wei, Huang Lu-Qi
School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China.
Key Laboratory of Dao-di Herbs, National Resources Center for Chinses Materia Medica, China Academy of Chinese Medicinal Sciences, Beijing 100700, China.
Zhongguo Zhong Yao Za Zhi. 2016 Aug;41(16):2953-2957. doi: 10.4268/cjcmm20161602.
CRISPR/Cas9 genome editing technology is a newly discovered genome editing technology in recent years.It has been widely used in many fields such as gene therapy, gene function research, animal model-making,cropvariety improvement and so on. This article briefly introduces the CRISPR/Cas9 genome editing system, and discusses its potential applications in the research of medicinal plants, including functional genomics studies, secondary metabolism and synthetic biology research of important active components and molecular breeding research. CRISPR/Cas9 genome editing technology provides a new method for the research of medicinal plants.
CRISPR/Cas9基因组编辑技术是近年来新发现的一种基因组编辑技术。它已广泛应用于基因治疗、基因功能研究、动物模型构建、作物品种改良等诸多领域。本文简要介绍了CRISPR/Cas9基因组编辑系统，并探讨了其在药用植物研究中的潜在应用，包括功能基因组学研究、重要活性成分的次生代谢与合成生物学研究以及分子育种研究。CRISPR/Cas9基因组编辑技术为药用植物研究提供了一种新方法。
