Suppr超能文献

鼻塞在持续气道正压通气(CPAP)常规使用的耐受性降低方面是否起作用?

Does nasal congestion have a role in decreased resistance to regular CPAP usage?

作者信息

İriz Ayşe, Düzlü Mehmet, Köktürk Oğuz, Kemaloğlu Yusuf Kemal, Eravcı Fakih Cihat, Zorlu Mehmet Ekrem, Karamert Recep

机构信息

Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Gazi University, Beşevler, 06500, Ankara, Turkey.

Department of Pulmonary Disease, Faculty of Medicine, Gazi University, Ankara, Turkey.

出版信息

Eur Arch Otorhinolaryngol. 2017 Nov;274(11):4031-4034. doi: 10.1007/s00405-017-4744-z. Epub 2017 Sep 18.

Abstract

Nasal obstruction is known to cause resistance to continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea syndrome (OSAS). In this paper, short- and long-term nasal congestion in OSAS patients receiving CPAP treatment were evaluated with acoustic rhinometry (AR). A total of 36 patients with moderate-to-severe OSAS, diagnosed with polysomnography were included in the study. Ten healthy subjects without OSAS constituted the control group. Pre-treatment nasal patency were measured with AR in all participants. 26 patients used the recommended CPAP treatment. Ten patients did not accept CPAP treatment. The AR test was repeated for all the subjects after 1 and 3 months except the 3rd month's measurements of the control group. There was no statistically significant difference between the initial minimum cross-sectional area (MCA) measurements of OSAS patients, using or not using CPAP, and the control group (P > 0.05). However, the first month MCA measurements of patients receiving CPAP were found to be significantly decreased compared with the initial values (P < 0.001). There was no significant change in the first and third months MCA values in the control group and patients who did not use CPAP (P > 0.05). No significant difference revealed in the 3rd month MCA measurements of the patients using CPAP compared with the initial values (P > 0.05). In this study, the increased nasal congestion, which is thought to be the cause of CPAP resistance, was objectively demonstrated in OSAS patients using CPAP. In addition, the nasal congestion developing at the first month was shown to disappear over time, supporting the opinion that patient compliance in CPAP treatment is expected to increase after regular device usage.

摘要

已知鼻阻塞会导致阻塞性睡眠呼吸暂停综合征(OSAS)患者对持续气道正压通气(CPAP)治疗产生抵抗。在本文中,采用鼻声反射(AR)对接受CPAP治疗的OSAS患者的短期和长期鼻充血情况进行了评估。共有36例经多导睡眠图诊断为中重度OSAS的患者纳入本研究。10名无OSAS的健康受试者构成对照组。对所有参与者进行治疗前鼻通畅度的AR测量。26例患者采用推荐的CPAP治疗。10例患者未接受CPAP治疗。除对照组第3个月的测量外,所有受试者在1个月和3个月后重复进行AR测试。使用或未使用CPAP的OSAS患者与对照组的初始最小横截面积(MCA)测量值之间无统计学显著差异(P>0.05)。然而,发现接受CPAP治疗的患者第1个月的MCA测量值与初始值相比显著降低(P<0.001)。对照组和未使用CPAP的患者在第1个月和第3个月的MCA值无显著变化(P>0.05)。使用CPAP的患者第3个月的MCA测量值与初始值相比无显著差异(P>0.05)。在本研究中,被认为是CPAP抵抗原因的鼻充血增加在使用CPAP的OSAS患者中得到了客观证实。此外,第1个月出现的鼻充血随时间推移逐渐消失,这支持了这样一种观点,即定期使用设备后,CPAP治疗的患者依从性有望提高。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验