意大利猪圆环病毒3型的检测与基因特征分析
Detection and genetic characterization of Porcine circovirus type 3 in Italy.
作者信息
Faccini S, Barbieri I, Gilioli A, Sala G, Gibelli L R, Moreno A, Sacchi C, Rosignoli C, Franzini G, Nigrelli A
机构信息
Diagnostic Unit of Mantova, IZSLER, Mantova (MN), Italy.
Genomic Unit, IZSLER, Brescia (BS), Italy.
出版信息
Transbound Emerg Dis. 2017 Dec;64(6):1661-1664. doi: 10.1111/tbed.12714. Epub 2017 Sep 17.
Porcine circovirus type 3 (PCV3) was recently proposed as a new porcine circovirus. It has been described by researchers in the USA and China and associated with porcine dermatitis and nephropathy syndrome, reproductive failure and systemic inflammation disease. The study reports the occurrence of the new virus in Italy. PCV3 was detected in the tissues of foetuses and stillborn piglets coming from two farms located in the Po Valley. The genome sequences of the two Italian strains share 99.7% to 97.8% of nucleotide identity with those available in GenBank. Results strengthen the hypothesis of PCV3 as a new emerging porcine circovirus, widespread all over the world. It follows the urgency of investigating in depth epidemiology and pathogenicity associated with this new virus.
猪圆环病毒3型（PCV3）最近被提议作为一种新的猪圆环病毒。美国和中国的研究人员对其进行了描述，并发现它与猪皮炎和肾病综合征、繁殖障碍及全身性炎症疾病有关。该研究报告了这种新病毒在意大利的出现情况。在来自波河河谷两个农场的胎儿和死产仔猪组织中检测到了PCV3。这两个意大利毒株的基因组序列与GenBank中已有的序列核苷酸同一性为99.7%至97.8%。研究结果强化了PCV3是一种新兴的、在全球广泛传播的猪圆环病毒这一假说。因此，深入调查与这种新病毒相关的流行病学和致病性变得刻不容缓。
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