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Effect of a somatostatin analogue, SMS 201-995, on 133Xe clearance from colonic mucosa in unanesthetized man.

作者信息

Mortensen P E, Olsen J, Bousfield R, Agerskov K, Christiansen J

机构信息

Dept. of Surgery D, Glostrup Hospital, University of Copenhagen, Denmark.

出版信息

Scand J Gastroenterol. 1987 Nov;22(9):1056-8. doi: 10.3109/00365528708991956.

Abstract

The effect of intravenous bolus injection of the somatostatin analogue SMS 201-995 on mucosal and submucosal blood flow was studied with the local 133Xe clearance technique in eight subjects. Mucosal and submucosal blood flow decreased by 33% after injection of SMS 201-995. These observations suggest that SMS 201-995, like somatostatin, inhibits splanchnic blood flow.

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