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体外循环后恶性高热的延迟发生

Delayed Development of Malignant Hyperthermia Following Cardiopulmonary Bypass.

作者信息

Sams Stephen Hall, Revilla Stephen, Stahl David Lawrence

机构信息

1 The Ohio State University Wexner Medical Center, Columbus, OH, USA.

出版信息

Semin Cardiothorac Vasc Anesth. 2018 Mar;22(1):95-99. doi: 10.1177/1089253217732128. Epub 2017 Sep 18.

DOI:10.1177/1089253217732128
PMID:28922985
Abstract

Malignant hyperthermia (MH) is a rare but potentially life-threatening disorder encountered during general anesthesia. The use of cardiopulmonary bypass during cardiac surgery can obscure many of the cardinal signs and symptoms of MH. The development of postoperative MH following cardiac surgery is rare, but anesthesiologists and intensivists must maintain a high index of suspicion in order to make a prompt diagnosis. Initiation and tailored maintenance of MH therapy must also consider the complex physiologic changes of patients in the immediate post-cardiac surgery period. In this article, we present a case of the development of postoperative MH in the cardiac intensive care unit after elective open heart surgery with cardiopulmonary bypass.

摘要

恶性高热(MH)是一种在全身麻醉期间罕见但可能危及生命的疾病。心脏手术期间使用体外循环可能会掩盖MH的许多主要体征和症状。心脏手术后发生术后MH的情况很少见,但麻醉医生和重症监护医生必须保持高度的怀疑指数以便及时做出诊断。MH治疗的启动和针对性维持还必须考虑心脏手术后即刻患者复杂的生理变化。在本文中,我们介绍了一例在择期体外循环心脏直视手术后心脏重症监护病房发生术后MH的病例。

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