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肝脏、小肠及多器官移植后非血管化腹直肌筋膜的应用:单中心系列研究的长期随访

Use of Nonvascularized Abdominal Rectus Fascia After Liver, Small Bowel, and Multiorgan Transplantation: Long-Term Follow-up of a Single-Center Series.

作者信息

Farinelli P A, Rubio J S, Padín J M, Rumbo C, Solar H, Ramisch D, Gondolesi G E

机构信息

Intestinal Failure, Rehabilitation and Transplant Unit, Hepatology, Hepato-Pancreato-Biliary Surgery and Liver Transplant Unit, Multiorgan Transplant Institute, Hospital Universitario Fundación Favaloro, Buenos Aires, Argentina.

Intestinal Failure, Rehabilitation and Transplant Unit, Hepatology, Hepato-Pancreato-Biliary Surgery and Liver Transplant Unit, Multiorgan Transplant Institute, Hospital Universitario Fundación Favaloro, Buenos Aires, Argentina.

出版信息

Transplant Proc. 2017 Oct;49(8):1810-1814. doi: 10.1016/j.transproceed.2017.05.012.

Abstract

BACKGROUND

The abdominal wall may be severely compromised in the vast majority of intestinal and multiorgan transplant candidates, and sometimes as a consequence of complex liver transplantation. Multiple options have been described to overcome this problem, varying from component separation to the extreme need of performing an abdominal wall transplantation. The aim of the present paper is to report the largest and longest-term results of patients that received an abdominal rectus fascia (ARF) after liver, intestinal, or multiorgan transplantation at a single transplant center.

METHODS

This is a retrospective report of a prospectively collected dataset of all the patients that received ARF during liver, isolated intestine, combined, or multiorgan transplantation at Fundación Favaloro from May 2006 to June 2016.

RESULTS

A total of 19 out of 528 patients (3.5%) that underwent abdominal organ transplant received an ARF graft: 17 patients after receiving an intestine-containing graft, and 2 after liver retransplantations. Three patients required changing the ARF, 2 with a synthetic mesh and 1 with another ARF. Five patients required late reoperations: A relaparotomy was performed by transecting the ARF without encountering adhesions on the inner ARF surface. None of the 2 patients who received liver retransplantations and ARF developed acute or chronic ventral defects.

CONCLUSIONS

The use of ARF is a simple and reliable surgical option to close abdominal wall defects during transplantation, the fascia adequately incorporates to the abdominal wall, allowing it to be transected and resutured in the long term and preserving the integrity of the peritoneal layer.

摘要

背景

绝大多数肠道和多器官移植候选者的腹壁可能受到严重损害,有时这是复杂肝移植的结果。已经描述了多种方法来克服这一问题,从成分分离到进行腹壁移植的极端需求。本文的目的是报告在单个移植中心接受肝、肠或多器官移植后接受腹直肌筋膜(ARF)的患者的最大规模和最长随访结果。

方法

这是一份对2006年5月至2016年6月在法瓦洛罗基金会接受肝、孤立肠、联合或多器官移植期间接受ARF的所有患者的前瞻性收集数据集的回顾性报告。

结果

528例接受腹部器官移植的患者中有19例(3.5%)接受了ARF移植:17例接受含肠移植后,2例接受肝再次移植后。3例患者需要更换ARF,2例使用合成补片,1例使用另一块ARF。5例患者需要后期再次手术:通过横断ARF进行再次剖腹手术,未在内侧ARF表面遇到粘连。接受肝再次移植和ARF的2例患者均未出现急性或慢性腹壁缺损。

结论

使用ARF是移植期间闭合腹壁缺损的一种简单可靠的手术选择,该筋膜能充分融入腹壁,使其能够长期横断和重新缝合,并保持腹膜层的完整性。

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