Justo I, Marcacuzco A, Caso O, Manrique A, Calvo J, García-Sesma A, Nutu A, García-Conde M, Cambra F, Loinaz C, Jiménez-Romero C
General Surgery Department. HPB Surgery and Abdominal Organ Transplantation Unit. "Doce de Octubre" University Hospital, Instituto de Investigación (imas12), Complutense University Madrid, Madrid, Spain.
General Surgery Department. HPB Surgery and Abdominal Organ Transplantation Unit. "Doce de Octubre" University Hospital, Instituto de Investigación (imas12), Complutense University Madrid, Madrid, Spain.
Transplant Proc. 2020 Jun;52(5):1468-1471. doi: 10.1016/j.transproceed.2020.01.081. Epub 2020 Mar 21.
Abdominal wall transplant is developed in the context of intestinal and multivisceral transplant, in which it is often impossible to perform a primary wall closure. Despite the fact that abdominal wall closure is not as consequential in liver transplant, there are circumstances in which it might determine the success of the liver graft, especially in situations that compromise the abdominal cavity and facilitate an abdominal compartment syndrome. CASE 1: A 14-year-old girl suffering from cryptogenic cirrhosis with severe portal hypertension that causes ascites and severe malnutrition. Uneventful liver transplant, with a graft procured from a 14-year-old donor. At the time of wall closure it was decided to implant a nonvascularized fascia graft to supplement the right side of the transverse incision, with a 17 x 7 cm defect. This required reintervention after 4 months for biliary stricture. At that point, the wall graft was almost completely integrated into the native tissue. CASE 2: A 63-year-old man, transplanted for hepatitis C virus+ hepatocellular carcinoma+ nonocclusive portal thrombosis. Thirty-six hours after transplant the patient developed portal thrombosis. Thrombectomy and closure with biological mesh were performed. After 24 hours he was reoperated on for abdominal compartment syndrome and temporary closure with a Bogotá bag. Six days later he underwent omentectomy, intestinal decompression, and left components separation, identifying a 25 x 20 cm defect. For definitive closure, a nonvascularized fascia graft procured from a different donor was used, accomplishing a reduction in intra-abdominal pressure. Nonvascularized fascia transplantation is an interesting alternative in liver transplant recipients with abdominal wall closure difficulties.
腹壁移植是在肠道和多脏器移植的背景下发展起来的,在这些移植手术中,通常无法进行一期腹壁关闭。尽管腹壁关闭在肝移植中并非至关重要,但在某些情况下,它可能决定肝移植的成功与否,尤其是在那些影响腹腔并易引发腹腔间隔室综合征的情况下。病例1:一名14岁女孩,患有隐源性肝硬化,伴有严重门静脉高压,导致腹水和严重营养不良。肝移植手术顺利,移植物取自一名14岁的供体。在关闭腹壁时,决定植入一块无血管化的筋膜移植物,以补充横切口右侧17×7厘米的缺损。4个月后因胆管狭窄需要再次干预。此时,腹壁移植物几乎已完全融入自体组织。病例2:一名63岁男性,因丙型肝炎病毒阳性、肝细胞癌和非闭塞性门静脉血栓形成而接受移植。移植后36小时,患者发生门静脉血栓形成。进行了血栓切除术并用生物补片关闭。24小时后,因腹腔间隔室综合征再次手术,并用波哥大袋临时关闭。6天后,他接受了大网膜切除术、肠道减压和左侧成分分离术,发现有一个25×20厘米的缺损。为了进行确定性关闭,使用了取自另一名供体的无血管化筋膜移植物,降低了腹腔内压力。对于腹壁关闭困难的肝移植受者,无血管化筋膜移植是一种有趣的选择。