Kawahara Ichiro, Toyoda Keisuke, Hirose Makoto, Kitagawa Naoki
Department of Neurosurgery, Nagasaki Rosai Hospital.
No Shinkei Geka. 2017 Sep;45(9):805-810. doi: 10.11477/mf.1436203597.
Cerebral venous sinus thrombosis(CVST)is a rare condition accounting for <1% of all strokes. It has been linked to a multitude of risk factors, including infections, oral contraceptive use, coronary disease, malignant disease, trauma, surgery, coagulopathy and several others. However, the association between hyperthyroidism and CVST is poorly understood. We describe here a rare case of CVST, secondary to subclinical Basedow disease. A 68-year-old woman with general fatigue, headache, speech disturbance and slow behavior was admitted to our hospital. Computed tomography(CT)and magnetic resonance imaging revealed a fresh infarction in the left temporal lobe, and CT angiography revealed filling defects of superior sagittal sinus and transverse sinus. Moreover, the patient was diagnosed with Basedow disease for the first time, by examination for tachycardia. This case suggests that it is essential to have a new awareness that hyperthyroidism is an important risk factor for CVST.
脑静脉窦血栓形成（CVST）是一种罕见疾病，占所有中风的比例不到1%。它与多种危险因素有关，包括感染、口服避孕药的使用、冠状动脉疾病、恶性疾病、创伤、手术、凝血病等。然而，甲状腺功能亢进与CVST之间的关联尚不清楚。我们在此描述一例继发于亚临床巴塞多病的CVST罕见病例。一名68岁女性因全身乏力、头痛、言语障碍和行为迟缓入住我院。计算机断层扫描（CT）和磁共振成像显示左侧颞叶有新鲜梗死灶，CT血管造影显示上矢状窦和横窦充盈缺损。此外，通过心动过速检查，该患者首次被诊断为巴塞多病。该病例表明，必须重新认识到甲状腺功能亢进是CVST的一个重要危险因素。
