Department of Internal Medicine (Neurology), School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
BMJ Case Rep. 2020 Dec 9;13(12):e236730. doi: 10.1136/bcr-2020-236730.
Cerebral venous sinus thrombosis (CVST) is caused by either acquired or inherited pro-thrombotic states. Hyperthyroidism is a less recognised predisposing factor of CVST, and the causality has been debated. We report a case of a life-threatening CVST in a 40-year-old woman, with uncommon dual risk factors: hyperthyroidism and advanced squamous cell carcinoma of the cervix. CVST should be considered as a differential diagnosis when a patient with hyperthyroidism presents with new-onset headache or other neurological symptoms. Further assessment to elucidate other covert risk factors may need to be continuously carried out, when the causal relationship of one apparent cause has not been well established.
脑静脉窦血栓形成（CVST）可由获得性或遗传性促血栓形成状态引起。甲状腺功能亢进症是 CVST 的一个不太被认识的诱发因素，其因果关系存在争议。我们报告了一例危及生命的 CVST 发生在一名 40 岁女性，其具有不常见的双重危险因素：甲状腺功能亢进症和晚期宫颈鳞状细胞癌。当患有甲状腺功能亢进症的患者出现新发头痛或其他神经系统症状时，应考虑 CVST 作为鉴别诊断。当一个明显病因的因果关系尚未得到充分确立时，可能需要持续进行进一步评估以阐明其他潜在的危险因素。
