玻璃体内药物注射过程中的意外情况——三例报告
Surprises during intravitreal drug delivery-a report of three cases.
作者信息
Venkatesh Pradeep, Chawla Rohan, Shah Bhavin, Garg Sat Pal
机构信息
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
出版信息
Digit J Ophthalmol. 2017 Mar 15;23(1):33-35. doi: 10.5693/djo.02.2016.12.002. eCollection 2017.
We describe 3 cases with unusual events during and after intravitreal injection of dexamethasone intravitreal implants and bevacizumab. In case 1, delayed release of the safety stop of a dexamethasone intravitreal implant injector led to impaction and retinal break formation. Timely recognition and laser treatment prevented further retinal complications. In case 2, reinjection of a second dexamethasone intravitreal implant from the same site as the first injection was noted to dislodge the remnant of the previous implant from the vitreous base. In case 3, translucent floating particles were noted in the vitreous after intravitreal injection of bevacizumab from ampules procured from our dispensing pharmacy.
我们描述了3例在玻璃体内注射地塞米松玻璃体内植入物和贝伐单抗期间及之后发生异常事件的病例。病例1中，地塞米松玻璃体内植入物注射器的安全止动装置延迟释放导致了植入物嵌顿和视网膜裂孔形成。及时识别并进行激光治疗预防了进一步的视网膜并发症。病例2中，在与首次注射相同的部位再次注射第二枚地塞米松玻璃体内植入物时，发现将先前植入物的残余部分从玻璃体基底部挤出。病例3中，从我们药房分发的安瓿瓶中抽取贝伐单抗进行玻璃体内注射后，在玻璃体内发现了半透明的漂浮颗粒。
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