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玻璃体内注射地塞米松植入术后黄斑外视网膜裂孔：病例报告

Extramacular Retinal Hole Following Intravitreal Dexamethasone Implant: Case Report.

作者信息

Ekinci Cansu, Kayıran Alp, Özdemir Hakan

机构信息

Bezmialem Vakıf University Faculty of Medicine, Department of Ophthalmology, İstanbul, Turkey

Yeditepe University Ophthalmology Research and Application Center, Department of Ophthalmology, İstanbul, Turkey

出版信息

Turk J Ophthalmol. 2019 Jun 27;49(3):175-177. doi: 10.4274/tjo.galenos.2019.98975.

DOI:10.4274/tjo.galenos.2019.98975
PMID:31245982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6624461/
Abstract

The intravitreal dexamethasone implant Ozurdex is indicated for the treatment of macular edema due to diabetes and branch retinal vein occlusion. While the most common ocular side effects are elevated intraocular pressure and cataract formation, rare complications related to the injection have been reported. We present a case with extramacular retinal hole after Ozurdex injection.

摘要

玻璃体内注射地塞米松植入剂Ozurdex适用于治疗糖尿病性黄斑水肿和视网膜分支静脉阻塞所致的黄斑水肿。虽然最常见的眼部副作用是眼压升高和白内障形成，但与注射相关的罕见并发症也有报道。我们报告1例Ozurdex注射后出现黄斑外视网膜裂孔的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67a9/6624461/71043f957c9e/TJO-49-175-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67a9/6624461/b5cde49cc57d/TJO-49-175-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67a9/6624461/a9c24164ca00/TJO-49-175-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67a9/6624461/71043f957c9e/TJO-49-175-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67a9/6624461/b5cde49cc57d/TJO-49-175-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67a9/6624461/a9c24164ca00/TJO-49-175-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67a9/6624461/71043f957c9e/TJO-49-175-g3.jpg

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Clin Ophthalmol. 2022 Apr 6;16:1019-1045. doi: 10.2147/OPTH.S209395. eCollection 2022.
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[Loss of vision after intravitreal dexamethasone injection in a vitrectomized eye].

本文引用的文献

1
"Magic Bullet": Eccentric Macular Hole as a Complication from Dexamethasone Implant Insertion.“魔弹”：地塞米松植入术引发的黄斑中心凹旁裂孔并发症
Case Rep Ophthalmol Med. 2016;2016:1706234. doi: 10.1155/2016/1706234. Epub 2016 Oct 5.
2
Common and Rare Ocular Side-effects of the Dexamethasone Implant.地塞米松植入物的常见和罕见眼部副作用。
Ocul Immunol Inflamm. 2017 Dec;25(6):834-840. doi: 10.1080/09273948.2016.1184284. Epub 2016 Jul 5.
3
Release and velocity of micronized dexamethasone implants with an intravitreal drug delivery system: kinematic analysis with a high-speed camera.
[玻璃体切除术后眼内注射地塞米松后视力丧失]
Ophthalmologe. 2021 Oct;118(10):1051-1053. doi: 10.1007/s00347-021-01328-1. Epub 2021 Mar 12.
微粉化地塞米松植入物与玻璃体内药物输送系统的释放和速度：高速摄像的运动学分析。
Retina. 2012 Nov-Dec;32(10):2133-40. doi: 10.1097/IAE.0b013e31825699e5.
4
Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion.随机、假手术对照试验研究地塞米松眼内植入剂治疗视网膜静脉阻塞所致黄斑水肿患者。
Ophthalmology. 2010 Jun;117(6):1134-1146.e3. doi: 10.1016/j.ophtha.2010.03.032. Epub 2010 Apr 24.