一名阻塞性睡眠呼吸暂停低通气综合征患者使用持续气道正压通气机后出现角膜新生血管伴脂质角膜病变
Corneal Neovascularization with Associated Lipid Keratopathy in a Patient with Obstructive Sleep Apnea-Hypopnea Syndrome Using a Continuous Positive Airway Pressure Machine.
作者信息
Oikonomakis Konstantinos, Petrelli Myrsini, Andreanos Konstantinos, Mouchtouris Andreas, Petrou Petros, Georgalas Ilias, Papaconstantinou Dimitrios, Kymionis George
机构信息
First Department of Ophthalmology, University of Athens, General Hospital of Athens "G. Gennimatas", Athens, Greece.
Faculty of Biology and Medicine, University of Lausanne, Fondation Asile des Aveugles, Hôpital Ophtalmique Jules-Gonin, Lausanne, Switzerland.
出版信息
Case Rep Ophthalmol. 2017 Aug 3;8(2):416-420. doi: 10.1159/000478925. eCollection 2017 May-Aug.
OBJECTIVE
To report a case of corneal neovascularization with secondary lipid keratopathy in a patient treated with continuous positive airway pressure (CPAP) for obstructive sleep apnea-hypopnea syndrome (OSAHS).
CASE REPORT
A 49-year-old male had been diagnosed with obstructive sleep apnea syndrome 10 years ago and has been treated with the application of a CPAP machine during night sleep ever since. For the past year, the patient had been complaining for ocular irritation and excessive tearing of the left eye on awakening. Slit-lamp biomicroscopy revealed the presence of neovascularization and lipid exudation in the inferior third of the cornea of the left eye. Ocular patching during night sleep resulted in recession of the reported symptoms and shrinkage of the neovascularization, while the area of lipid exudation ceased to enlarge.
CONCLUSION
To the best of our knowledge, this is the first report of corneal neovascularization in a patient using a CPAP machine for OSAHS.
目的
报告1例阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者使用持续气道正压通气（CPAP）治疗后出现角膜新生血管并继发脂质角膜病变的病例。
病例报告
一名49岁男性于10年前被诊断为阻塞性睡眠呼吸暂停综合征，此后一直通过在夜间睡眠时使用CPAP机器进行治疗。在过去一年中，该患者一直抱怨醒来时左眼有眼部刺激感和流泪过多。裂隙灯生物显微镜检查显示左眼角膜下三分之一处存在新生血管和脂质渗出。夜间睡眠时眼部遮盖使报告的症状减轻，新生血管缩小，而脂质渗出区域不再扩大。
结论
据我们所知，这是首例关于使用CPAP机器治疗OSAHS的患者出现角膜新生血管的报告。
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