睡眠呼吸暂停患者在接受持续气道正压通气治疗时发生的非动脉炎性前部缺血性视神经病变。
Nonarteritic anterior ischemic optic neuropathy in patients with sleep apnea while being treated with continuous positive airway pressure.
作者信息
Behbehani Raed, Mathews Michaela K, Sergott Robert C, Savino Peter J
机构信息
Neuroophthalmology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
出版信息
Am J Ophthalmol. 2005 Mar;139(3):518-21. doi: 10.1016/j.ajo.2004.11.004.
PURPOSE
To report three cases of nonarteritic anterior ischemic optic neuropathy (NAION) that occurred in patients with sleep apnea syndrome (SAS) while being treated with continuous positive airway pressure (CPAP).
DESIGN
A prospective, noncomparative case series.
METHODS
Prospective review of 108 patients with NAION diagnosed between 2002 and 2003 to identify any patients who developed NAION while being treated for SAS with CPAP.
RESULTS
One patient had bilateral sequential NAION and two patients had unilateral NAION despite treatment with CPAP for SAS. All the patients were being treated with CPAP for a period ranging from 4 months to 6 years before the onset of NAION.
CONCLUSIONS
In this series, CPAP did not prevent the development of NAION in SAS patients. Larger observational studies are needed to study the benefit of CPAP in preventing NAION in patients with SAS.
目的
报告3例睡眠呼吸暂停综合征（SAS）患者在接受持续气道正压通气（CPAP）治疗时发生非动脉炎性前部缺血性视神经病变（NAION）的病例。
设计
一项前瞻性、非对照病例系列研究。
方法
对2002年至2003年间确诊的108例NAION患者进行前瞻性回顾，以确定在接受CPAP治疗SAS期间发生NAION的患者。
结果
1例患者发生双侧序贯性NAION，2例患者发生单侧NAION，尽管他们正在接受CPAP治疗SAS。所有患者在NAION发作前接受CPAP治疗的时间为4个月至6年。
结论
在本系列研究中，CPAP未能预防SAS患者发生NAION。需要开展更大规模的观察性研究，以探讨CPAP在预防SAS患者发生NAION方面的益处。
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