Yue John K, Sing David C, Sharma Sourabh, Upadhyayula Pavan S, Winkler Ethan A, Shaw Jeremy D, Metz Lionel N
a Department of Orthopedic Surgery , University of California San Francisco , San Francisco , CA , USA.
b Department of Neurological Surgery , University of California San Francisco , San Francisco , CA , USA.
Neurol Res. 2017 Dec;39(12):1066-1072. doi: 10.1080/01616412.2017.1378298. Epub 2017 Sep 19.
Objectives Risk factors portending poor outcome following elective spine deformity fusion remain in need of characterization and stratification in the elderly population. Methods Cases aged ≥60 years who underwent elective posterior or anterior-posterior ('combined') fusion were extracted from the American College of Surgeons National Surgical Quality Improvement Program years 2007-2013 and analyzed by surgical cohort (posterior vs. combined). The 30-day outcomes included operation time, hospital length of stay (HLOS), perioperative complications, and discharge destination. Multivariable regressions controlling for demographic/clinical variables were performed. Odds ratios (OR) and mean differences (B) were reported with 95% confidence intervals (CI). Results A total of 881 cases (18.2% combined; 81.8% posterior) aged 70 ± 6.2 years, 32.8% male, and 87.2% Caucasian were included. Posterior fusions associated with extreme body habitus (obese class II/III and underweight; P = 0.027), functional independence (97.5% vs. 91.8%; P = 0.010), and multi-level fusions (7-12 levels: 24.8% vs. 18.1%; ≥13 levels: 8.9% vs. 3.1%; P = 0.004). Overall operation time was 338.0 ± 150.2-min and HLOS 7.4 ± 6.6-days; 17.1% suffered early complications and 54.5% were discharged home. On multivariable analysis, combined (B = 63.8-min; P < 0.001), and multi-level fusions (7-12: 61.0-min; P < 0.001; ≥13: 133.8-min; p < 0.001) associated with increased operation time. HLOS increased for multi-level fusions (7-12 levels: 1.3-days; P = 0.012; ≥13 levels: 2.2-days; P = 0.008). Overall complications did not differ by cohort or levels; on post hoc analysis combined fusions associated with pneumonia (OR = 3.05; P = 0.008). Multi-level fusions showed decreased odds of discharge home (7-12 levels: OR = 0.57; P = 0.003; ≥13-levels: OR = 0.41; P = 0.003). Conclusions The 30-day outcomes and early perioperative complications are comparable for posterior vs. combined approaches to correct deformity in the elderly. Multi-level fusions are associated with increased operation time, HLOS, and discharge to higher level of care.
在老年人群中,仍需要对择期脊柱畸形融合术后预后不良的危险因素进行特征描述和分层。方法:从美国外科医师学会国家外科质量改进计划2007 - 2013年的数据中提取年龄≥60岁且接受择期后路或前后路(“联合”)融合手术的病例,并按手术队列(后路与联合)进行分析。30天的结局指标包括手术时间、住院时间(HLOS)、围手术期并发症及出院去向。进行了控制人口统计学/临床变量的多变量回归分析。报告了优势比(OR)和平均差(B)及其95%置信区间(CI)。结果:共纳入881例病例(18.2%为联合手术;81.8%为后路手术),年龄70±6.2岁,男性占32.8%,白种人占87.2%。后路融合与极端体型(肥胖II/III级和体重过轻;P = 0.027)、功能独立(97.5%对91.8%;P = 0.010)以及多节段融合(7 - 12节段:24.8%对18.1%;≥13节段:8.9%对3.1%;P = 0.004)相关。总体手术时间为338.0±150.2分钟,HLOS为7.4±6.6天;17.1%发生早期并发症,54.5%出院回家。多变量分析显示,联合手术(B = 63.8分钟;P < 0.001)和多节段融合(7 - 12节段:61.0分钟;P < 0.001;≥13节段:133.8分钟;P < 0.001)与手术时间延长相关。多节段融合的HLOS增加(7 - 12节段:1.3天;P = 0.012;≥13节段:2.2天;P = 0.008)。总体并发症在不同队列或节段之间无差异;事后分析显示联合融合与肺炎相关(OR = 3.05;P = 0.008)。多节段融合显示出院回家的几率降低(7 - 12节段:OR = 0.57;P = 0.003;≥13节段:OR = 0.41;P = 0.003)。结论:在老年人中,后路与联合手术矫正畸形的30天结局和早期围手术期并发症具有可比性。多节段融合与手术时间延长、HLOS增加以及转至更高护理级别相关。