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后路融合术治疗成人脊柱畸形后,手术时间对围手术期并发症的预测作用大于手术侵袭性:是否需要加快速度?

After Posterior Fusions for Adult Spinal Deformity, Operative Time is More Predictive of Perioperative Morbidity, Rather Than Surgical Invasiveness: A Need for Speed?

机构信息

Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY.

Department of Orthopedics and Rehabilitation, Yale School of Medicine, New Haven, CT.

出版信息

Spine (Phila Pa 1976). 2017 Dec 15;42(24):1880-1887. doi: 10.1097/BRS.0000000000002243.

Abstract

STUDY DESIGN

A retrospective cohort study.

OBJECTIVE

The aim of this study was to determine the independent effects of operative time and surgical invasiveness on perioperative outcomes after posterior spinal fusions for adult spinal deformity.

SUMMARY OF BACKGROUND DATA

Morbidity is high after posterior fusions for adult spinal deformity. Although previous reports have demonstrated an association between perioperative outcomes and the extent of correction and fusion (number of posterior levels fused, pelvic fixation, combined anterior-posterior fusion), no study has looked at the independent effects of the surgical invasiveness after controlling for operative time.

METHODS

All adult patients, undergoing posterior spinal fusion for spinal deformity, were identified in the 2010 to 2014 National Surgical Quality Improvement Program (NSQIP) database. Multivariate analysis was used to determine the independent effects of longer operative timing and the surgical invasiveness (number of levels fused, anterior or transforaminal interbody fusions, osteotomies, and pelvic fixation) on 30-day complications.

RESULTS

A total of 1540 patients undergoing posterior spinal fusion for adult spinal deformity were identified. The overall rate of complications was 15.3%. In multivariate analysis, greater operative timing was associated with increased inpatient complications [odds ratio (95% confidence interval, 95% CI) from 2.23 (1.25-3.98) for 7-8 hours to 4.46 (2.61-7.64) for 9+ hours; P < 0.001]. Although the number of levels fused, anterior/interbody fusions, osteotomies, and pelvic fixation were associated with complications on bivariate analysis, these factors were not associated with increased complications in multivariate analysis when controlling for other factors such as operative time.

CONCLUSION

For adult deformity surgery, longer operative time appears to be a better predictor of the overall rate perioperative complications than surgical invasiveness in multivariate analysis. Rather than avoidance of a more extensive and invasive surgical procedure, which may be indicated to improve alignment and stability, these data suggest the importance of safely and efficiently minimizing overall operative time.

LEVEL OF EVIDENCE

摘要

研究设计

回顾性队列研究。

目的

本研究旨在确定手术时间和手术侵袭性对成人脊柱畸形后路脊柱融合术后围手术期结果的独立影响。

背景资料概要

成人脊柱畸形后路融合术后发病率较高。尽管之前的报告表明围手术期结果与矫正和融合程度(融合的后路节段数、骨盆固定、前后联合融合)之间存在关联,但尚无研究在控制手术时间的情况下观察手术侵袭性的独立影响。

方法

在 2010 年至 2014 年国家手术质量改进计划(NSQIP)数据库中确定所有接受脊柱畸形后路脊柱融合术的成年患者。使用多变量分析确定较长手术时间和手术侵袭性(融合的节段数、前路或经椎间孔融合、截骨术和骨盆固定)对 30 天并发症的独立影响。

结果

共确定了 1540 例接受成人脊柱畸形后路脊柱融合术的患者。总体并发症发生率为 15.3%。多变量分析显示,手术时间延长与住院并发症增加相关[比值比(95%置信区间,95%CI)从 7-8 小时的 2.23(1.25-3.98)增加到 9+小时的 4.46(2.61-7.64);P<0.001]。尽管融合的节段数、前路/椎间融合、截骨术和骨盆固定在单变量分析中与并发症相关,但在多变量分析中控制手术时间等其他因素时,这些因素与并发症增加无关。

结论

对于成人畸形手术,手术时间延长似乎比手术侵袭性更能预测多变量分析中围手术期总体并发症发生率。这些数据表明,安全有效地尽量减少整体手术时间的重要性,而不是避免更广泛和侵袭性的手术程序,这可能有助于改善对准和稳定性。

证据水平

4 级。

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